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Attenuation of SARS-CoV-2 replication and associated inflammation by concomitant targeting of viral and host cap 2'-O-ribose methyltransferases.
Bergant V, Yamada S, Grass V, Tsukamoto Y, Lavacca T, Krey K, Mühlhofer MT, Wittmann S, Ensser A, Herrmann A, Vom Hemdt A, Tomita Y, Matsuyama S, Hirokawa T, Huang Y, Piras A, Jakwerth CA, Oelsner M, Thieme S, Graf A, Krebs S, Blum H, Kümmerer BM, Stukalov A, Schmidt-Weber CB, Igarashi M, Gramberg T, Pichlmair A, Kato H. Bergant V, et al. Among authors: pichlmair a. EMBO J. 2022 Sep 1;41(17):e111608. doi: 10.15252/embj.2022111608. Epub 2022 Jul 25. EMBO J. 2022. PMID: 35833542 Free PMC article.
Gambling with Flu: "All in" to Maximize Reward.
Stukalov A, Pichlmair A. Stukalov A, et al. Among authors: pichlmair a. Cell Host Microbe. 2015 Dec 9;18(6):643-5. doi: 10.1016/j.chom.2015.11.010. Cell Host Microbe. 2015. PMID: 26651939 Free article.
An orthogonal proteomic survey uncovers novel Zika virus host factors.
Scaturro P, Stukalov A, Haas DA, Cortese M, Draganova K, Płaszczyca A, Bartenschlager R, Götz M, Pichlmair A. Scaturro P, et al. Among authors: pichlmair a. Nature. 2018 Sep;561(7722):253-257. doi: 10.1038/s41586-018-0484-5. Epub 2018 Sep 3. Nature. 2018. PMID: 30177828
The alternative cap-binding complex is required for antiviral defense in vivo.
Gebhardt A, Bergant V, Schnepf D, Moser M, Meiler A, Togbe D, Mackowiak C, Reinert LS, Paludan SR, Ryffel B, Stukalov A, Staeheli P, Pichlmair A. Gebhardt A, et al. Among authors: pichlmair a. PLoS Pathog. 2019 Dec 19;15(12):e1008155. doi: 10.1371/journal.ppat.1008155. eCollection 2019 Dec. PLoS Pathog. 2019. PMID: 31856218 Free PMC article.
Data, Reagents, Assays and Merits of Proteomics for SARS-CoV-2 Research and Testing.
Zecha J, Lee CY, Bayer FP, Meng C, Grass V, Zerweck J, Schnatbaum K, Michler T, Pichlmair A, Ludwig C, Kuster B. Zecha J, et al. Among authors: pichlmair a. Mol Cell Proteomics. 2020 Sep;19(9):1503-1522. doi: 10.1074/mcp.RA120.002164. Epub 2020 Jun 26. Mol Cell Proteomics. 2020. PMID: 32591346 Free PMC article.
Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing.
Sadegh S, Matschinske J, Blumenthal DB, Galindez G, Kacprowski T, List M, Nasirigerdeh R, Oubounyt M, Pichlmair A, Rose TD, Salgado-Albarrán M, Späth J, Stukalov A, Wenke NK, Yuan K, Pauling JK, Baumbach J. Sadegh S, et al. Among authors: pichlmair a. Nat Commun. 2020 Jul 14;11(1):3518. doi: 10.1038/s41467-020-17189-2. Nat Commun. 2020. PMID: 32665542 Free PMC article.
Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.
Stukalov A, Girault V, Grass V, Karayel O, Bergant V, Urban C, Haas DA, Huang Y, Oubraham L, Wang A, Hamad MS, Piras A, Hansen FM, Tanzer MC, Paron I, Zinzula L, Engleitner T, Reinecke M, Lavacca TM, Ehmann R, Wölfel R, Jores J, Kuster B, Protzer U, Rad R, Ziebuhr J, Thiel V, Scaturro P, Mann M, Pichlmair A. Stukalov A, et al. Among authors: pichlmair a. Nature. 2021 Jun;594(7862):246-252. doi: 10.1038/s41586-021-03493-4. Epub 2021 Apr 12. Nature. 2021. PMID: 33845483
98 results