Persaud A - Search Results

1

Elevated intracellular Na⁺ and osmolarity stimulate catalytic activity of the ubiquitin ligase Nedd4-2.

Persaud A, Jiang C, Liu Z, Kefalas G, Demian WL, Rotin D. Persaud A, et al. Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2122495119. doi: 10.1073/pnas.2122495119. Epub 2022 Jul 18. Proc Natl Acad Sci U S A. 2022. PMID: 35858421 Free PMC article.

2

Use of proteome arrays to globally identify substrates for E3 ubiquitin ligases.

Persaud A, Rotin D. Persaud A, et al. Methods Mol Biol. 2011;759:215-24. doi: 10.1007/978-1-61779-173-4_13. Methods Mol Biol. 2011. PMID: 21863490

3

Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays.

Persaud A, Alberts P, Amsen EM, Xiong X, Wasmuth J, Saadon Z, Fladd C, Parkinson J, Rotin D. Persaud A, et al. Mol Syst Biol. 2009;5:333. doi: 10.1038/msb.2009.85. Epub 2009 Dec 1. Mol Syst Biol. 2009. PMID: 19953087 Free PMC article.

4

Nedd4-1 binds and ubiquitylates activated FGFR1 to control its endocytosis and function.

Persaud A, Alberts P, Hayes M, Guettler S, Clarke I, Sicheri F, Dirks P, Ciruna B, Rotin D. Persaud A, et al. EMBO J. 2011 Jul 15;30(16):3259-73. doi: 10.1038/emboj.2011.234. EMBO J. 2011. PMID: 21765395 Free PMC article.

5

Protein tyrosine phosphatase σ targets apical junction complex proteins in the intestine and regulates epithelial permeability.

Murchie R, Guo CH, Persaud A, Muise A, Rotin D. Murchie R, et al. Among authors: persaud a. Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):693-8. doi: 10.1073/pnas.1315017111. Epub 2014 Jan 2. Proc Natl Acad Sci U S A. 2014. PMID: 24385580 Free PMC article.

6

Tyrosine phosphorylation of NEDD4 activates its ubiquitin ligase activity.

Persaud A, Alberts P, Mari S, Tong J, Murchie R, Maspero E, Safi F, Moran MF, Polo S, Rotin D. Persaud A, et al. Sci Signal. 2014 Oct 7;7(346):ra95. doi: 10.1126/scisignal.2005290. Sci Signal. 2014. PMID: 25292214

7

Rsp5/Nedd4 is the main ubiquitin ligase that targets cytosolic misfolded proteins following heat stress.

Fang NN, Chan GT, Zhu M, Comyn SA, Persaud A, Deshaies RJ, Rotin D, Gsponer J, Mayor T. Fang NN, et al. Among authors: persaud a. Nat Cell Biol. 2014 Dec;16(12):1227-37. doi: 10.1038/ncb3054. Epub 2014 Oct 26. Nat Cell Biol. 2014. PMID: 25344756 Free PMC article.

8

System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.

Zhang W, Wu KP, Sartori MA, Kamadurai HB, Ordureau A, Jiang C, Mercredi PY, Murchie R, Hu J, Persaud A, Mukherjee M, Li N, Doye A, Walker JR, Sheng Y, Hao Z, Li Y, Brown KR, Lemichez E, Chen J, Tong Y, Harper JW, Moffat J, Rotin D, Schulman BA, Sidhu SS. Zhang W, et al. Among authors: persaud a. Mol Cell. 2016 Apr 7;62(1):121-36. doi: 10.1016/j.molcel.2016.02.005. Epub 2016 Mar 3. Mol Cell. 2016. PMID: 26949039 Free PMC article.

9

Ubiquitylation-dependent oligomerization regulates activity of Nedd4 ligases.

Attali I, Tobelaim WS, Persaud A, Motamedchaboki K, Simpson-Lavy KJ, Mashahreh B, Levin-Kravets O, Keren-Kaplan T, Pilzer I, Kupiec M, Wiener R, Wolf DA, Rotin D, Prag G. Attali I, et al. Among authors: persaud a. EMBO J. 2017 Feb 15;36(4):425-440. doi: 10.15252/embj.201694314. Epub 2017 Jan 9. EMBO J. 2017. PMID: 28069708 Free PMC article.

10

Regulation of SH3PX1 by dNedd4-long at the Drosophila neuromuscular junction.

Wasserman SS, Shteiman-Kotler A, Harris K, Iliadi KG, Persaud A, Zhong Y, Zhang Y, Fang X, Boulianne GL, Stewart B, Rotin D. Wasserman SS, et al. Among authors: persaud a. J Biol Chem. 2019 Feb 1;294(5):1739-1752. doi: 10.1074/jbc.RA118.005161. Epub 2018 Dec 5. J Biol Chem. 2019. PMID: 30518551 Free PMC article.

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