Goldman JE - Search Results

1

Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex.

Wu X, Sosunov AA, Lado W, Teoh JJ, Ham A, Li H, Al-Dalahmah O, Gill BJA, Arancio O, Schevon CA, Frankel WN, McKhann GM 2nd, Sulzer D, Goldman JE, Tang G. Wu X, et al. Among authors: goldman je. Cell Rep. 2022 Jul 19;40(3):111085. doi: 10.1016/j.celrep.2022.111085. Cell Rep. 2022. PMID: 35858542 Free PMC article.

2

Synergistic effects of the SAPK/JNK and the proteasome pathway on glial fibrillary acidic protein (GFAP) accumulation in Alexander disease.

Tang G, Xu Z, Goldman JE. Tang G, et al. Among authors: goldman je. J Biol Chem. 2006 Dec 15;281(50):38634-43. doi: 10.1074/jbc.M604942200. Epub 2006 Oct 10. J Biol Chem. 2006. PMID: 17038307 Free article.

3

Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways.

Tang G, Yue Z, Talloczy Z, Hagemann T, Cho W, Messing A, Sulzer DL, Goldman JE. Tang G, et al. Among authors: goldman je. Hum Mol Genet. 2008 Jun 1;17(11):1540-55. doi: 10.1093/hmg/ddn042. Epub 2008 Feb 14. Hum Mol Genet. 2008. PMID: 18276609 Free PMC article.

4

Adaptive autophagy in Alexander disease-affected astrocytes.

Tang G, Yue Z, Talloczy Z, Goldman JE. Tang G, et al. Among authors: goldman je. Autophagy. 2008 Jul;4(5):701-3. Epub 2008 Apr 3. Autophagy. 2008. PMID: 18414043 Review.

5

Oligomers of mutant glial fibrillary acidic protein (GFAP) Inhibit the proteasome system in alexander disease astrocytes, and the small heat shock protein alphaB-crystallin reverses the inhibition.

Tang G, Perng MD, Wilk S, Quinlan R, Goldman JE. Tang G, et al. Among authors: goldman je. J Biol Chem. 2010 Apr 2;285(14):10527-37. doi: 10.1074/jbc.M109.067975. Epub 2010 Jan 28. J Biol Chem. 2010. PMID: 20110364 Free PMC article.

6

Alexander disease mutant glial fibrillary acidic protein compromises glutamate transport in astrocytes.

Tian R, Wu X, Hagemann TL, Sosunov AA, Messing A, McKhann GM, Goldman JE. Tian R, et al. Among authors: goldman je. J Neuropathol Exp Neurol. 2010 Apr;69(4):335-45. doi: 10.1097/NEN.0b013e3181d3cb52. J Neuropathol Exp Neurol. 2010. PMID: 20448479 Free PMC article.

7

Phenotypic conversions of "protoplasmic" to "reactive" astrocytes in Alexander disease.

Sosunov AA, Guilfoyle E, Wu X, McKhann GM 2nd, Goldman JE. Sosunov AA, et al. Among authors: goldman je. J Neurosci. 2013 Apr 24;33(17):7439-50. doi: 10.1523/JNEUROSCI.4506-12.2013. J Neurosci. 2013. PMID: 23616550 Free PMC article.

8

Phenotypic heterogeneity and plasticity of isocortical and hippocampal astrocytes in the human brain.

Sosunov AA, Wu X, Tsankova NM, Guilfoyle E, McKhann GM 2nd, Goldman JE. Sosunov AA, et al. Among authors: goldman je. J Neurosci. 2014 Feb 5;34(6):2285-98. doi: 10.1523/JNEUROSCI.4037-13.2014. J Neurosci. 2014. PMID: 24501367 Free PMC article.

9

Epileptogenic but MRI-normal perituberal tissue in Tuberous Sclerosis Complex contains tuber-specific abnormalities.

Sosunov AA, McGovern RA, Mikell CB, Wu X, Coughlin DG, Crino PB, Weiner HL, Ghatan S, Goldman JE, McKhann GM 2nd. Sosunov AA, et al. Among authors: goldman je. Acta Neuropathol Commun. 2015 Apr 2;3:17. doi: 10.1186/s40478-015-0191-5. Acta Neuropathol Commun. 2015. PMID: 25853525 Free PMC article.

10

The origin of Rosenthal fibers and their contributions to astrocyte pathology in Alexander disease.

Sosunov AA, McKhann GM 2nd, Goldman JE. Sosunov AA, et al. Among authors: goldman je. Acta Neuropathol Commun. 2017 Mar 31;5(1):27. doi: 10.1186/s40478-017-0425-9. Acta Neuropathol Commun. 2017. PMID: 28359321 Free PMC article.

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