Bogacz M - Search Results

1

Development of Urea-Bond-Containing Michael Acceptors as Antitrypanosomal Agents Targeting Rhodesain.

Previti S, Ettari R, Calcaterra E, Di Chio C, Ravichandran R, Zimmer C, Hammerschmidt S, Wagner A, Bogacz M, Cosconati S, Schirmeister T, Zappalà M. Previti S, et al. Among authors: bogacz m. ACS Med Chem Lett. 2022 Jun 30;13(7):1083-1090. doi: 10.1021/acsmedchemlett.2c00084. eCollection 2022 Jul 14. ACS Med Chem Lett. 2022. PMID: 35859868 Free PMC article.

2

Development of Reduced Peptide Bond Pseudopeptide Michael Acceptors for the Treatment of Human African Trypanosomiasis.

Previti S, Ettari R, Di Chio C, Ravichandran R, Bogacz M, Hellmich UA, Schirmeister T, Cosconati S, Zappalà M. Previti S, et al. Among authors: bogacz m. Molecules. 2022 Jun 11;27(12):3765. doi: 10.3390/molecules27123765. Molecules. 2022. PMID: 35744891 Free PMC article.

3

Drug Combination Studies of the Dipeptide Nitrile CD24 with Curcumin: A New Strategy to Synergistically Inhibit Rhodesain of Trypanosoma brucei rhodesiense.

Di Chio C, Previti S, De Luca F, Bogacz M, Zimmer C, Wagner A, Schirmeister T, Zappalà M, Ettari R. Di Chio C, et al. Among authors: bogacz m. Int J Mol Sci. 2022 Nov 21;23(22):14470. doi: 10.3390/ijms232214470. Int J Mol Sci. 2022. PMID: 36430948 Free PMC article.

4

Total Synthesis and Structure Correction of the Cyclic Lipodepsipeptide Orfamide A.

Bando Y, Hou Y, Seyfarth L, Probst J, Götze S, Bogacz M, Hellmich UA, Stallforth P, Mittag M, Arndt HD. Bando Y, et al. Among authors: bogacz m. Chemistry. 2022 Apr 6;28(20):e202104417. doi: 10.1002/chem.202104417. Epub 2022 Mar 9. Chemistry. 2022. PMID: 35199896 Free PMC article.

5

The mitochondrial peroxiredoxin displays distinct roles in different developmental stages of African trypanosomes.

Bogacz M, Dirdjaja N, Wimmer B, Habich C, Krauth-Siegel RL. Bogacz M, et al. Redox Biol. 2020 Jul;34:101547. doi: 10.1016/j.redox.2020.101547. Epub 2020 Apr 29. Redox Biol. 2020. PMID: 32388269 Free PMC article.

6

Catalytic properties, localization, and in vivo role of Px IV, a novel tryparedoxin peroxidase of Trypanosoma brucei.

Liu I, Bogacz M, Schaffroth C, Dirdjaja N, Krauth-Siegel RL. Liu I, et al. Among authors: bogacz m. Mol Biochem Parasitol. 2016 Jun;207(2):84-8. doi: 10.1016/j.molbiopara.2016.05.013. Epub 2016 Jun 1. Mol Biochem Parasitol. 2016. PMID: 27262262

7

The cytosolic or the mitochondrial glutathione peroxidase-type tryparedoxin peroxidase is sufficient to protect procyclic Trypanosoma brucei from iron-mediated mitochondrial damage and lysis.

Schaffroth C, Bogacz M, Dirdjaja N, Nißen A, Krauth-Siegel RL. Schaffroth C, et al. Among authors: bogacz m. Mol Microbiol. 2016 Jan;99(1):172-87. doi: 10.1111/mmi.13223. Epub 2015 Oct 20. Mol Microbiol. 2016. PMID: 26374473 Free article.

8

Tryparedoxin peroxidase-deficiency commits trypanosomes to ferroptosis-type cell death.

Bogacz M, Krauth-Siegel RL. Bogacz M, et al. Elife. 2018 Jul 26;7:e37503. doi: 10.7554/eLife.37503. Elife. 2018. PMID: 30047863 Free PMC article.

9

A tryparedoxin-coupled biosensor reveals a mitochondrial trypanothione metabolism in trypanosomes.

Ebersoll S, Bogacz M, Günter LM, Dick TP, Krauth-Siegel RL. Ebersoll S, et al. Among authors: bogacz m. Elife. 2020 Jan 31;9:e53227. doi: 10.7554/eLife.53227. Elife. 2020. PMID: 32003744 Free PMC article.

10

Development of Novel Peptidyl Nitriles Targeting Rhodesain and Falcipain-2 for the Treatment of Sleeping Sickness and Malaria.

Di Chio C, Starvaggi J, Totaro N, Previti S, Natale B, Cosconati S, Bogacz M, Schirmeister T, Legac J, Rosenthal PJ, Zappalà M, Ettari R. Di Chio C, et al. Among authors: bogacz m. Int J Mol Sci. 2024 Apr 17;25(8):4410. doi: 10.3390/ijms25084410. Int J Mol Sci. 2024. PMID: 38673995 Free PMC article.

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