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A novel receptor-binding domain (RBD)-based mRNA vaccine against SARS-CoV-2.
Tai W, Zhang X, Drelich A, Shi J, Hsu JC, Luchsinger L, Hillyer CD, Tseng CK, Jiang S, Du L. Tai W, et al. Among authors: tseng ck. Cell Res. 2020 Oct;30(10):932-935. doi: 10.1038/s41422-020-0387-5. Epub 2020 Aug 5. Cell Res. 2020. PMID: 32759966 Free PMC article. No abstract available.
A Speedy Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors.
Yang KS, Ma XR, Ma Y, Alugubelli YR, Scott DA, Vatansever EC, Drelich AK, Sankaran B, Geng ZZ, Blankenship LR, Ward HE, Sheng YJ, Hsu JC, Kratch KC, Zhao B, Hayatshahi HS, Liu J, Li P, Fierke CA, Tseng CK, Xu S, Liu WR. Yang KS, et al. Among authors: tseng ck. bioRxiv [Preprint]. 2020 Jul 28:2020.07.28.223784. doi: 10.1101/2020.07.28.223784. bioRxiv. 2020. Update in: ChemMedChem. 2021 Mar 18;16(6):942-948. doi: 10.1002/cmdc.202000924 PMID: 32766582 Free PMC article. Updated. Preprint.
Rapid identification of a human antibody with high prophylactic and therapeutic efficacy in three animal models of SARS-CoV-2 infection.
Li W, Chen C, Drelich A, Martinez DR, Gralinski LE, Sun Z, Schäfer A, Kulkarni SS, Liu X, Leist SR, Zhelev DV, Zhang L, Kim YJ, Peterson EC, Conard A, Mellors JW, Tseng CK, Falzarano D, Baric RS, Dimitrov DS. Li W, et al. Among authors: tseng ck. Proc Natl Acad Sci U S A. 2020 Nov 24;117(47):29832-29838. doi: 10.1073/pnas.2010197117. Epub 2020 Nov 2. Proc Natl Acad Sci U S A. 2020. PMID: 33139569 Free PMC article.
A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*.
Yang KS, Ma XR, Ma Y, Alugubelli YR, Scott DA, Vatansever EC, Drelich AK, Sankaran B, Geng ZZ, Blankenship LR, Ward HE, Sheng YJ, Hsu JC, Kratch KC, Zhao B, Hayatshahi HS, Liu J, Li P, Fierke CA, Tseng CK, Xu S, Liu WR. Yang KS, et al. Among authors: tseng ck. ChemMedChem. 2021 Mar 18;16(6):942-948. doi: 10.1002/cmdc.202000924. Epub 2020 Dec 10. ChemMedChem. 2021. PMID: 33283984 Free PMC article.
Potent in vitro anti-SARS-CoV-2 activity by gallinamide A and analogues via inhibition of cathepsin L.
Ashhurst AS, Tang AH, Fajtová P, Yoon M, Aggarwal A, Stoye A, Larance M, Beretta L, Drelich A, Skinner D, Li L, Meek TD, McKerrow JH, Hook V, Tseng CK, Turville S, Gerwick WH, O'Donoghue AJ, Payne RJ. Ashhurst AS, et al. Among authors: tseng ck. bioRxiv [Preprint]. 2020 Dec 24:2020.12.23.424111. doi: 10.1101/2020.12.23.424111. bioRxiv. 2020. Update in: J Med Chem. 2022 Feb 24;65(4):2956-2970. doi: 10.1021/acs.jmedchem.1c01494 PMID: 33398273 Free PMC article. Updated. Preprint.
Bepridil is potent against SARS-CoV-2 in vitro.
Vatansever EC, Yang KS, Drelich AK, Kratch KC, Cho CC, Kempaiah KR, Hsu JC, Mellott DM, Xu S, Tseng CK, Liu WR. Vatansever EC, et al. Among authors: tseng ck. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2012201118. doi: 10.1073/pnas.2012201118. Proc Natl Acad Sci U S A. 2021. PMID: 33597253 Free PMC article.
292 results