Le W - Search Results

1

Heparin induces α-synuclein to form new fibril polymorphs with attenuated neuropathology.

Tao Y, Sun Y, Lv S, Xia W, Zhao K, Xu Q, Zhao Q, He L, Le W, Wang Y, Liu C, Li D. Tao Y, et al. Among authors: le w. Nat Commun. 2022 Jul 22;13(1):4226. doi: 10.1038/s41467-022-31790-7. Nat Commun. 2022. PMID: 35869048 Free PMC article.

2

Intrastriatal injection of Parkinson's disease intestine and vagus lysates initiates α-synucleinopathy in rat brain.

Yang Z, Wang Y, Wei M, Li S, Jia C, Cheng C, Al-Nusaif M, Zhang J, Liu C, Le W. Yang Z, et al. Among authors: le w. Cell Death Dis. 2023 Jan 5;14(1):4. doi: 10.1038/s41419-022-05531-z. Cell Death Dis. 2023. PMID: 36604420 Free PMC article.

3

Terahertz Irradiation Improves Cognitive Impairments and Attenuates Alzheimer's Neuropathology in the APP^SWE/PS1^DE9 Mouse: A Novel Therapeutic Intervention for Alzheimer's Disease.

Zhang J, Chen Y, Zhao Y, Wang P, Ding H, Liu C, Lyu J, Le W. Zhang J, et al. Among authors: le w. Neurosci Bull. 2024 Jul;40(7):857-871. doi: 10.1007/s12264-023-01145-3. Epub 2023 Nov 16. Neurosci Bull. 2024. PMID: 37971654 Free PMC article.

4

Phosphorylation and O-GlcNAcylation at the same α-synuclein site generate distinct fibril structures.

Hu J, Xia W, Zeng S, Lim YJ, Tao Y, Sun Y, Zhao L, Wang H, Le W, Li D, Zhang S, Liu C, Li YM. Hu J, et al. Among authors: le w. Nat Commun. 2024 Mar 27;15(1):2677. doi: 10.1038/s41467-024-46898-1. Nat Commun. 2024. PMID: 38538591 Free PMC article.

5

Halogen doped graphene quantum dots modulate TDP-43 phase separation and aggregation in the nucleus.

Zhang H, Guo H, Li D, Zhang Y, Zhang S, Kang W, Liu C, Le W, Wang L, Li D, Dai B. Zhang H, et al. Among authors: le w. Nat Commun. 2024 Apr 6;15(1):2980. doi: 10.1038/s41467-024-47167-x. Nat Commun. 2024. PMID: 38582774 Free PMC article.

6

Fecal microbiota from patients with Parkinson's disease intensifies inflammation and neurodegeneration in A53T mice.

Yang H, Shao Y, Hu Y, Qian J, Wang P, Tian L, Ni Y, Li S, Al-Nusaif M, Liu C, Le W. Yang H, et al. Among authors: le w. CNS Neurosci Ther. 2024 Aug;30(8):e70003. doi: 10.1111/cns.70003. CNS Neurosci Ther. 2024. PMID: 39161161 Free PMC article.

7

Pathological characteristics of axons and alterations of proteomic and lipidomic profiles in midbrain dopaminergic neurodegeneration induced by WDR45-deficiency.

Wang P, Shao Y, Al-Nusaif M, Zhang J, Yang H, Yang Y, Kim K, Li S, Liu C, Cai H, Le W. Wang P, et al. Among authors: le w. Mol Neurodegener. 2024 Aug 26;19(1):62. doi: 10.1186/s13024-024-00746-4. Mol Neurodegener. 2024. PMID: 39183331 Free PMC article.

8

Olfactory dysfunction and neurotransmitter disturbance in olfactory bulb of transgenic mice expressing human A53T mutant α-synuclein.

Zhang S, Xiao Q, Le W. Zhang S, et al. Among authors: le w. PLoS One. 2015 Mar 23;10(3):e0119928. doi: 10.1371/journal.pone.0119928. eCollection 2015. PLoS One. 2015. PMID: 25799501 Free PMC article.

9

HDAC6-mediated Hsp90 deacetylation reduces aggregation and toxicity of the protein alpha-synuclein by regulating chaperone-mediated autophagy.

Du Y, Yang X, Li Z, Le W, Hao Y, Song Y, Wang F, Guan Y. Du Y, et al. Among authors: le w. Neurochem Int. 2021 Oct;149:105141. doi: 10.1016/j.neuint.2021.105141. Epub 2021 Jul 21. Neurochem Int. 2021. PMID: 34298079

10

Altered Motor Performance, Sleep EEG, and Parkinson's Disease Pathology Induced by Chronic Sleep Deprivation in Lrrk2^G2019S Mice.

Liu X, Yu H, Wang Y, Li S, Cheng C, Al-Nusaif M, Le W. Liu X, et al. Among authors: le w. Neurosci Bull. 2022 Oct;38(10):1170-1182. doi: 10.1007/s12264-022-00881-2. Epub 2022 May 25. Neurosci Bull. 2022. PMID: 35612787 Free PMC article.

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