Lees JA - Search Results

1

MITF deficiency and oncogenic GNAQ each promote proliferation programs in zebrafish melanocyte lineage cells.

Phelps GB, Amsterdam A, Hagen HR, García NZ, Lees JA. Phelps GB, et al. Among authors: lees ja. Pigment Cell Melanoma Res. 2022 Sep;35(5):539-547. doi: 10.1111/pcmr.13057. Epub 2022 Jul 28. Pigment Cell Melanoma Res. 2022. PMID: 35869673 Free PMC article.

2

Many ribosomal protein genes are cancer genes in zebrafish.

Amsterdam A, Sadler KC, Lai K, Farrington S, Bronson RT, Lees JA, Hopkins N. Amsterdam A, et al. Among authors: lees ja. PLoS Biol. 2004 May;2(5):E139. doi: 10.1371/journal.pbio.0020139. Epub 2004 May 11. PLoS Biol. 2004. PMID: 15138505 Free PMC article.

3

DTL/CDT2 is essential for both CDT1 regulation and the early G2/M checkpoint.

Sansam CL, Shepard JL, Lai K, Ianari A, Danielian PS, Amsterdam A, Hopkins N, Lees JA. Sansam CL, et al. Among authors: lees ja. Genes Dev. 2006 Nov 15;20(22):3117-29. doi: 10.1101/gad.1482106. Epub 2006 Nov 3. Genes Dev. 2006. PMID: 17085480 Free PMC article.

4

Loss of p53 synthesis in zebrafish tumors with ribosomal protein gene mutations.

MacInnes AW, Amsterdam A, Whittaker CA, Hopkins N, Lees JA. MacInnes AW, et al. Among authors: lees ja. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10408-13. doi: 10.1073/pnas.0805036105. Epub 2008 Jul 18. Proc Natl Acad Sci U S A. 2008. PMID: 18641120 Free PMC article.

5

Many ribosomal protein mutations are associated with growth impairment and tumor predisposition in zebrafish.

Lai K, Amsterdam A, Farrington S, Bronson RT, Hopkins N, Lees JA. Lai K, et al. Among authors: lees ja. Dev Dyn. 2009 Jan;238(1):76-85. doi: 10.1002/dvdy.21815. Dev Dyn. 2009. PMID: 19097187 Free PMC article.

6

Zebrafish Hagoromo mutants up-regulate fgf8 postembryonically and develop neuroblastoma.

Amsterdam A, Lai K, Komisarczuk AZ, Becker TS, Bronson RT, Hopkins N, Lees JA. Amsterdam A, et al. Among authors: lees ja. Mol Cancer Res. 2009 Jun;7(6):841-50. doi: 10.1158/1541-7786.MCR-08-0555. Epub 2009 Jun 16. Mol Cancer Res. 2009. PMID: 19531571 Free PMC article.

7

A vertebrate gene, ticrr, is an essential checkpoint and replication regulator.

Sansam CL, Cruz NM, Danielian PS, Amsterdam A, Lau ML, Hopkins N, Lees JA. Sansam CL, et al. Among authors: lees ja. Genes Dev. 2010 Jan 15;24(2):183-94. doi: 10.1101/gad.1860310. Genes Dev. 2010. PMID: 20080954 Free PMC article.

8

Highly aneuploid zebrafish malignant peripheral nerve sheath tumors have genetic alterations similar to human cancers.

Zhang G, Hoersch S, Amsterdam A, Whittaker CA, Lees JA, Hopkins N. Zhang G, et al. Among authors: lees ja. Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):16940-5. doi: 10.1073/pnas.1011548107. Epub 2010 Sep 13. Proc Natl Acad Sci U S A. 2010. PMID: 20837522 Free PMC article.

9

Comparative oncogenomic analysis of copy number alterations in human and zebrafish tumors enables cancer driver discovery.

Zhang G, Hoersch S, Amsterdam A, Whittaker CA, Beert E, Catchen JM, Farrington S, Postlethwait JH, Legius E, Hopkins N, Lees JA. Zhang G, et al. Among authors: lees ja. PLoS Genet. 2013 Aug;9(8):e1003734. doi: 10.1371/journal.pgen.1003734. Epub 2013 Aug 29. PLoS Genet. 2013. PMID: 24009526 Free PMC article.

10

Variations in dysfunction of sister chromatid cohesion in esco2 mutant zebrafish reflect the phenotypic diversity of Roberts syndrome.

Percival SM, Thomas HR, Amsterdam A, Carroll AJ, Lees JA, Yost HJ, Parant JM. Percival SM, et al. Among authors: lees ja. Dis Model Mech. 2015 Aug 1;8(8):941-55. doi: 10.1242/dmm.019059. Epub 2015 Jun 4. Dis Model Mech. 2015. PMID: 26044958 Free PMC article.

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