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Regenerating islet-derived protein 3α: A promising therapy for diabetes. Preliminary data in rodents and in humans.
Le Lay A, Philippe E, Roth F, Sanchez-Archidona AR, Mehl F, Denom J, Prasad R, Asplund O, Hansson O, Ibberson M, Andreelli F, Santoro L, Amouyal P, Amouyal G, Brechot C, Jamot L, Cruciani-Guglielmacci C, Magnan C. Le Lay A, et al. Among authors: hansson o. Heliyon. 2022 Jul 16;8(7):e09944. doi: 10.1016/j.heliyon.2022.e09944. eCollection 2022 Jul. Heliyon. 2022. PMID: 35874080 Free PMC article.
Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D.
Viñuela A, Varshney A, van de Bunt M, Prasad RB, Asplund O, Bennett A, Boehnke M, Brown AA, Erdos MR, Fadista J, Hansson O, Hatem G, Howald C, Iyengar AK, Johnson P, Krus U, MacDonald PE, Mahajan A, Manning Fox JE, Narisu N, Nylander V, Orchard P, Oskolkov N, Panousis NI, Payne A, Stitzel ML, Vadlamudi S, Welch R, Collins FS, Mohlke KL, Gloyn AL, Scott LJ, Dermitzakis ET, Groop L, Parker SCJ, McCarthy MI. Viñuela A, et al. Among authors: hansson o. Nat Commun. 2020 Sep 30;11(1):4912. doi: 10.1038/s41467-020-18581-8. Nat Commun. 2020. PMID: 32999275 Free PMC article.
SCRT1 is a novel beta cell transcription factor with insulin regulatory properties.
Chriett S, Lindqvist A, Shcherbina L, Edlund A, Abels M, Asplund O, Martínez López JA, Ottosson-Laakso E, Hatem G, Prasad RB, Groop L, Eliasson L, Hansson O, Wierup N. Chriett S, et al. Among authors: hansson o. Mol Cell Endocrinol. 2021 Feb 5;521:111107. doi: 10.1016/j.mce.2020.111107. Epub 2020 Dec 10. Mol Cell Endocrinol. 2021. PMID: 33309639
Mapping the Cord Blood Transcriptome of Pregnancies Affected by Early Maternal Anemia to Identify Signatures of Fetal Programming.
Hatem G, Hjort L, Asplund O, Minja DTR, Msemo OA, Møller SL, Lavstsen T, Groth-Grunnet L, Lusingu JPA, Hansson O, Christensen DL, Vaag AA, Artner I, Theander T, Groop L, Schmiegelow C, Bygbjerg IC, Prasad RB. Hatem G, et al. Among authors: hansson o. J Clin Endocrinol Metab. 2022 Apr 19;107(5):1303-1316. doi: 10.1210/clinem/dgac010. J Clin Endocrinol Metab. 2022. PMID: 35021220 Free PMC article.
Islet Gene View-a tool to facilitate islet research.
Asplund O, Storm P, Chandra V, Hatem G, Ottosson-Laakso E, Mansour-Aly D, Krus U, Ibrahim H, Ahlqvist E, Tuomi T, Renström E, Korsgren O, Wierup N, Ibberson M, Solimena M, Marchetti P, Wollheim C, Artner I, Mulder H, Hansson O, Otonkoski T, Groop L, Prasad RB. Asplund O, et al. Among authors: hansson o. Life Sci Alliance. 2022 Aug 10;5(12):e202201376. doi: 10.26508/lsa.202201376. Life Sci Alliance. 2022. PMID: 35948367 Free PMC article.
Multiomics profiling of DNA methylation, microRNA, and mRNA in skeletal muscle from monozygotic twin pairs discordant for type 2 diabetes identifies dysregulated genes controlling metabolism.
Ling C, Vavakova M, Ahmad Mir B, Säll J, Perfilyev A, Martin M, Jansson PA, Davegårdh C, Asplund O, Hansson O, Vaag A, Nilsson E. Ling C, et al. Among authors: hansson o. BMC Med. 2024 Dec 2;22(1):572. doi: 10.1186/s12916-024-03789-y. BMC Med. 2024. PMID: 39623445 Free PMC article.
Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes.
Mahdi T, Hänzelmann S, Salehi A, Muhammed SJ, Reinbothe TM, Tang Y, Axelsson AS, Zhou Y, Jing X, Almgren P, Krus U, Taneera J, Blom AM, Lyssenko V, Esguerra JL, Hansson O, Eliasson L, Derry J, Zhang E, Wollheim CB, Groop L, Renström E, Rosengren AH. Mahdi T, et al. Among authors: hansson o. Cell Metab. 2012 Nov 7;16(5):625-33. doi: 10.1016/j.cmet.2012.10.009. Cell Metab. 2012. PMID: 23140642 Free article.
815 results