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Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage.
Deng H, Gao Y, Trappetti V, Hertig D, Karatkevich D, Losmanova T, Urzi C, Ge H, Geest GA, Bruggmann R, Djonov V, Nuoffer JM, Vermathen P, Zamboni N, Riether C, Ochsenbein A, Peng RW, Kocher GJ, Schmid RA, Dorn P, Marti TM. Deng H, et al. Among authors: marti tm. Cell Mol Life Sci. 2022 Jul 25;79(8):445. doi: 10.1007/s00018-022-04453-5. Cell Mol Life Sci. 2022. PMID: 35877003 Free PMC article.
Toll-like receptor 4 activation attenuates profibrotic response in control lung fibroblasts but not in fibroblasts from patients with IPF.
Ebener S, Barnowski S, Wotzkow C, Marti TM, Lopez-Rodriguez E, Crestani B, Blank F, Schmid RA, Geiser T, Funke M. Ebener S, et al. Among authors: marti tm. Am J Physiol Lung Cell Mol Physiol. 2017 Jan 1;312(1):L42-L55. doi: 10.1152/ajplung.00119.2016. Epub 2016 Nov 4. Am J Physiol Lung Cell Mol Physiol. 2017. PMID: 27815256 Free article.
Increased PD-L1 expression and IL-6 secretion characterize human lung tumor-derived perivascular-like cells that promote vascular leakage in a perfusable microvasculature model.
Bichsel CA, Wang L, Froment L, Berezowska S, Müller S, Dorn P, Marti TM, Peng RW, Geiser T, Schmid RA, Guenat OT, Hall SRR. Bichsel CA, et al. Among authors: marti tm. Sci Rep. 2017 Sep 6;7(1):10636. doi: 10.1038/s41598-017-09928-1. Sci Rep. 2017. PMID: 28878242 Free PMC article.
Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma.
Xu D, Liang SQ, Yang H, Lüthi U, Riether C, Berezowska S, Marti TM, Hall SRR, Bruggmann R, Kocher GJ, Schmid RA, Peng RW. Xu D, et al. Among authors: marti tm. Br J Cancer. 2018 Jul;119(1):65-75. doi: 10.1038/s41416-018-0145-3. Epub 2018 Jun 20. Br J Cancer. 2018. PMID: 29921948 Free PMC article.
126 results