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SARS-CoV-2 impairs interferon production via NSP2-induced repression of mRNA translation.
Xu Z, Choi JH, Dai DL, Luo J, Ladak RJ, Li Q, Wang Y, Zhang C, Wiebe S, Liu ACH, Ran X, Yang J, Naeli P, Garzia A, Zhou L, Mahmood N, Deng Q, Elaish M, Lin R, Mahal LK, Hobman TC, Pelletier J, Alain T, Vidal SM, Duchaine T, Mazhab-Jafari MT, Mao X, Jafarnejad SM, Sonenberg N. Xu Z, et al. Among authors: vidal sm. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2204539119. doi: 10.1073/pnas.2204539119. Epub 2022 Jul 25. Proc Natl Acad Sci U S A. 2022. PMID: 35878012 Free PMC article.
N-ethyl-N-nitrosourea-induced mutation in ubiquitin-specific peptidase 18 causes hyperactivation of IFN-αß signaling and suppresses STAT4-induced IFN-γ production, resulting in increased susceptibility to Salmonella typhimurium.
Richer E, Prendergast C, Zhang DE, Qureshi ST, Vidal SM, Malo D. Richer E, et al. Among authors: vidal sm. J Immunol. 2010 Sep 15;185(6):3593-601. doi: 10.4049/jimmunol.1000890. Epub 2010 Aug 6. J Immunol. 2010. PMID: 20693420 Free PMC article.
125 results