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51 results

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Page 1
Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells.
Qasim W, Zhan H, Samarasinghe S, Adams S, Amrolia P, Stafford S, Butler K, Rivat C, Wright G, Somana K, Ghorashian S, Pinner D, Ahsan G, Gilmour K, Lucchini G, Inglott S, Mifsud W, Chiesa R, Peggs KS, Chan L, Farzeneh F, Thrasher AJ, Vora A, Pule M, Veys P. Qasim W, et al. Among authors: ghorashian s. Sci Transl Med. 2017 Jan 25;9(374):eaaj2013. doi: 10.1126/scitranslmed.aaj2013. Sci Transl Med. 2017. PMID: 28123068
A guide to manufacturing CAR T cell therapies.
Vormittag P, Gunn R, Ghorashian S, Veraitch FS. Vormittag P, et al. Among authors: ghorashian s. Curr Opin Biotechnol. 2018 Oct;53:164-181. doi: 10.1016/j.copbio.2018.01.025. Epub 2018 Feb 18. Curr Opin Biotechnol. 2018. PMID: 29462761 Review.
Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR.
Ghorashian S, Kramer AM, Onuoha S, Wright G, Bartram J, Richardson R, Albon SJ, Casanovas-Company J, Castro F, Popova B, Villanueva K, Yeung J, Vetharoy W, Guvenel A, Wawrzyniecka PA, Mekkaoui L, Cheung GW, Pinner D, Chu J, Lucchini G, Silva J, Ciocarlie O, Lazareva A, Inglott S, Gilmour KC, Ahsan G, Ferrari M, Manzoor S, Champion K, Brooks T, Lopes A, Hackshaw A, Farzaneh F, Chiesa R, Rao K, Bonney D, Samarasinghe S, Goulden N, Vora A, Veys P, Hough R, Wynn R, Pule MA, Amrolia PJ. Ghorashian S, et al. Nat Med. 2019 Sep;25(9):1408-1414. doi: 10.1038/s41591-019-0549-5. Epub 2019 Sep 2. Nat Med. 2019. PMID: 31477906 Clinical Trial.
Blinatumomab for infant acute lymphoblastic leukemia.
Clesham K, Rao V, Bartram J, Ancliff P, Ghorashian S, O'Connor D, Pavasovic V, Rao A, Samarasinghe S, Cummins M, Malone A, Patrick K, Bonney D, James B, Gibson B, Vora A. Clesham K, et al. Among authors: ghorashian s. Blood. 2020 Apr 23;135(17):1501-1504. doi: 10.1182/blood.2019004008. Blood. 2020. PMID: 32043146 Free article. No abstract available.
Remdesivir during induction chemotherapy for newly diagnosed paediatric acute lymphoblastic leukaemia with concomitant SARS-CoV-2 infection.
Orf K, Rogosic S, Dexter D, Ancliff P, Badle S, Brierley J, Cheng D, Dalton C, Dixon G, Du Pré P, Grandjean L, Ghorashian S, Mittal P, O'Connor D, Pavasovic V, Rao A, Samarasinghe S, Vora A, Bamford A, Bartram J. Orf K, et al. Among authors: ghorashian s. Br J Haematol. 2020 Sep;190(5):e274-e276. doi: 10.1111/bjh.17014. Epub 2020 Aug 23. Br J Haematol. 2020. PMID: 32652563 Free PMC article. No abstract available.
CD1a is rarely expressed in pediatric or adult relapsed/refractory T-ALL: implications for immunotherapy.
Leong S, Inglott S, Papaleonidopoulou F, Orfinada K, Ancliff P, Bartram J, Carpenter B, Fielding AK, Ghorashian S, Grandage V, Gupta R, Hough R, Khwaja A, Pavasovic V, Rao A, Samarasinghe S, Vora A, Mansour MR, O'Connor D. Leong S, et al. Among authors: ghorashian s. Blood Adv. 2020 Oct 13;4(19):4665-4668. doi: 10.1182/bloodadvances.2020002502. Blood Adv. 2020. PMID: 33002130 Free PMC article. No abstract available.
51 results