Park HG - Search Results

1

Optimization of 2-Aminoquinazolin-4-(3H)-one Derivatives as Potent Inhibitors of SARS-CoV-2: Improved Synthesis and Pharmacokinetic Properties.

Shin YS, Lee JY, Jeon S, Cho JE, Myung S, Jang MS, Kim S, Song JH, Kim HR, Park HG, Jeong LS, Park CM. Shin YS, et al. Among authors: park hg, park cm. Pharmaceuticals (Basel). 2022 Jul 4;15(7):831. doi: 10.3390/ph15070831. Pharmaceuticals (Basel). 2022. PMID: 35890130 Free PMC article.

2

Enantioselective Synthesis of Chiral α-Thio-Quaternary Stereogenic Centers via Phase-Transfer-Catalyzed α-Alkylation of α-Acylthiomalonates.

Ha MW, Lee JY, Kim D, Lee G, Lee JK, Hong S, Park HG. Ha MW, et al. Among authors: park hg. J Org Chem. 2018 Jan 19;83(2):1011-1018. doi: 10.1021/acs.joc.7b02605. Epub 2018 Jan 10. J Org Chem. 2018. PMID: 29262254

3

Novel SARS-CoV-2 entry inhibitors, 2-anilinoquinazolin-4(3H)-one derivatives, show potency as SARS-CoV-2 antivirals in a human ACE2 transgenic mouse model.

Ko M, Lee JY, Shin YS, Jeon S, Myung S, Cho JE, Jang MS, Song JH, Kim HR, Park HG, Park CM, Kim S. Ko M, et al. Among authors: park hg, park cm. J Med Virol. 2023 Jun;95(6):e28863. doi: 10.1002/jmv.28863. J Med Virol. 2023. PMID: 37310127

4

Synthesis and evaluation of N-arylindazole-3-carboxamide derivatives as novel antiviral agents against SARS-CoV-2.

Lee JY, Jeon S, Cho JE, Kim S, Kim HR, Park HG, Kim S, Park CM. Lee JY, et al. Among authors: park hg. Bioorg Med Chem Lett. 2024 Dec 1;114:130015. doi: 10.1016/j.bmcl.2024.130015. Epub 2024 Nov 1. Bioorg Med Chem Lett. 2024. PMID: 39489229 Free article.

5

Inhibition of DOT1L by Half-Selenopsammaplin A Analogs Suppresses Tumor Growth and EMT-Mediated Metastasis in Triple-Negative Breast Cancer.

Byun WS, Lee GH, Park HG, Lee SK. Byun WS, et al. Among authors: park hg. Pharmaceuticals (Basel). 2020 Dec 28;14(1):18. doi: 10.3390/ph14010018. Pharmaceuticals (Basel). 2020. PMID: 33379275 Free PMC article.

6

Synthesis and biological evaluation of picolinamides as potent inhibitors of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1).

Ryu JH, Kim S, Han HY, Son HJ, Lee HJ, Shin YA, Kim JS, Park HG. Ryu JH, et al. Among authors: park hg. Bioorg Med Chem Lett. 2015 Feb 1;25(3):695-700. doi: 10.1016/j.bmcl.2014.11.074. Epub 2014 Dec 5. Bioorg Med Chem Lett. 2015. PMID: 25529735

7

Synthesis and optimization of picolinamide derivatives as a novel class of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors.

Ryu JH, Kim S, Lee JA, Han HY, Son HJ, Lee HJ, Kim YH, Kim JS, Park HG. Ryu JH, et al. Among authors: park hg. Bioorg Med Chem Lett. 2015 Apr 15;25(8):1679-1683. doi: 10.1016/j.bmcl.2015.03.003. Epub 2015 Mar 10. Bioorg Med Chem Lett. 2015. PMID: 25800116

8

Efficient enantioselective total synthesis of (-)-horsfiline.

Hong S, Jung M, Park Y, Ha MW, Park C, Lee M, Park HG. Hong S, et al. Among authors: park hg, park c, park y. Chemistry. 2013 Jul 15;19(29):9599-605. doi: 10.1002/chem.201301008. Epub 2013 Jun 7. Chemistry. 2013. PMID: 23836402

9

Synthesis of 6-formyl-pyridine-2-carboxylate derivatives and their telomerase inhibitory activities.

Jew SS, Park BS, Lim DY, Kim MG, Chung IK, Kim JH, Hong CI, Kim JK, Park HJ, Lee JH, Park HG. Jew SS, et al. Among authors: park bs, park hg, park hj. Bioorg Med Chem Lett. 2003 Feb 24;13(4):609-12. doi: 10.1016/s0960-894x(02)01041-7. Bioorg Med Chem Lett. 2003. PMID: 12639541

10

Enantioselective Synthesis of (+)-Coerulescine by a Phase-Transfer Catalytic Allylation of Diphenylmethyl tert-Butyl α-(2-Nitrophenyl)Malonate.

Lee S, Yang J, Yang S, Lee G, Oh D, Ha MW, Hong S, Park HG. Lee S, et al. Among authors: park hg. Front Chem. 2020 Nov 12;8:577371. doi: 10.3389/fchem.2020.577371. eCollection 2020. Front Chem. 2020. PMID: 33282828 Free PMC article.

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