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Discovery of Clinical Candidate CHF-6366: A Novel Super-soft Dual Pharmacology Muscarinic Antagonist and β2 Agonist (MABA) for the Inhaled Treatment of Respiratory Diseases.
Carzaniga L, Linney ID, Rizzi A, Delcanale M, Schmidt W, Knight CK, Pastore F, Miglietta D, Carnini C, Cesari N, Riccardi B, Mileo V, Venturi L, Moretti E, Blackaby WP, Patacchini R, Accetta A, Biagetti M, Bassani F, Tondelli M, Murgo A, Battipaglia L, Villetti G, Puccini P, Catinella S, Civelli M, Rancati F. Carzaniga L, et al. Among authors: moretti e. J Med Chem. 2022 Aug 11;65(15):10233-10250. doi: 10.1021/acs.jmedchem.2c00609. Epub 2022 Jul 28. J Med Chem. 2022. PMID: 35901125
CHF6001 II: a novel phosphodiesterase 4 inhibitor, suitable for topical pulmonary administration--in vivo preclinical pharmacology profile defines a potent anti-inflammatory compound with a wide therapeutic window.
Villetti G, Carnini C, Battipaglia L, Preynat L, Bolzoni PT, Bassani F, Caruso P, Bergamaschi M, Pisano AR, Puviani V, Stellari FF, Cenacchi V, Volta R, Bertacche V, Mileo V, Bagnacani V, Moretti E, Puccini P, Catinella S, Facchinetti F, Sala A, Civelli M. Villetti G, et al. Among authors: moretti e. J Pharmacol Exp Ther. 2015 Mar;352(3):568-78. doi: 10.1124/jpet.114.220558. Epub 2015 Jan 9. J Pharmacol Exp Ther. 2015. PMID: 25576073
Designing Soluble PROTACs: Strategies and Preliminary Guidelines.
García Jiménez D, Rossi Sebastiano M, Vallaro M, Mileo V, Pizzirani D, Moretti E, Ermondi G, Caron G. García Jiménez D, et al. Among authors: moretti e. J Med Chem. 2022 Oct 13;65(19):12639-12649. doi: 10.1021/acs.jmedchem.2c00201. Epub 2022 Apr 25. J Med Chem. 2022. PMID: 35469399 Free PMC article.
Heptadecanoylcarnitine (C17) a novel candidate biomarker for newborn screening of propionic and methylmalonic acidemias.
Malvagia S, Haynes CA, Grisotto L, Ombrone D, Funghini S, Moretti E, McGreevy KS, Biggeri A, Guerrini R, Yahyaoui R, Garg U, Seeterlin M, Chace D, De Jesus VR, la Marca G. Malvagia S, et al. Among authors: moretti e. Clin Chim Acta. 2015 Oct 23;450:342-8. doi: 10.1016/j.cca.2015.09.012. Epub 2015 Sep 11. Clin Chim Acta. 2015. PMID: 26368264 Free PMC article.
The Role of Sleep Apnea in Postoperative Neurocognitive Disorders Among Older Noncardiac Surgery Patients: A Prospective Cohort Study.
Devinney MJ, Spector AR, Wright MC, Thomas J, Avasarala P, Moretti EW, Dominguez JE, Smith PJ, Whitson HE, Veasey SC, Mathew JP, Berger M; and the INTUIT Study Investigators. Devinney MJ, et al. Among authors: moretti ew. Anesth Analg. 2025 Jan 1;140(1):99-109. doi: 10.1213/ANE.0000000000007269. Epub 2024 Nov 22. Anesth Analg. 2025. PMID: 39688967
Prospective study on Oncotype DX® assay to assess recurrence risk in early ER-positive HER2-negative breast cancer patients with uncertain biological behavior by standard parameters and its impact on treatment recommendation: The POST trial.
Livraghi L, Martella F, Ghilli M, Angiolini C, Magnanini S, Moretti E, Bengala C, Risi E, Molinara E, Pazzagli I, Malorni L, Donati S, Gabellini S, Martignetti A, Giannessi P, Sanna G, Barellini L, Biagioni C, Boni L, Bianchi S, Roncella M, Biganzoli L. Livraghi L, et al. Among authors: moretti e. Eur J Cancer. 2024 Dec;213:115108. doi: 10.1016/j.ejca.2024.115108. Epub 2024 Oct 31. Eur J Cancer. 2024. PMID: 39522332 Free article.
544 results