Proschak E - Search Results

1

Compilation and evaluation of a fatty acid mimetics screening library.

Ehrler JHM, Brunst S, Tjaden A, Kilu W, Heering J, Hernandez-Olmos V, Krommes A, Kramer JS, Steinhilber D, Schubert-Zsilavecz M, Müller S, Merk D, Proschak E. Ehrler JHM, et al. Among authors: proschak e. Biochem Pharmacol. 2022 Oct;204:115191. doi: 10.1016/j.bcp.2022.115191. Epub 2022 Jul 27. Biochem Pharmacol. 2022. PMID: 35907497

2

Scaffold-hopping cascade yields potent inhibitors of 5-lipoxygenase.

Hofmann B, Franke L, Proschak E, Tanrikulu Y, Schneider P, Steinhilber D, Schneider G. Hofmann B, et al. Among authors: proschak e. ChemMedChem. 2008 Oct;3(10):1535-8. doi: 10.1002/cmdc.200800153. ChemMedChem. 2008. PMID: 18688907 No abstract available.

3

PhAST: pharmacophore alignment search tool.

Hähnke V, Hofmann B, Grgat T, Proschak E, Steinhilber D, Schneider G. Hähnke V, et al. Among authors: proschak e. J Comput Chem. 2009 Apr 15;30(5):761-71. doi: 10.1002/jcc.21095. J Comput Chem. 2009. PMID: 18727161

4

From molecular shape to potent bioactive agents I: bioisosteric replacement of molecular fragments.

Proschak E, Zettl H, Tanrikulu Y, Weisel M, Kriegl JM, Rau O, Schubert-Zsilavecz M, Schneider G. Proschak E, et al. ChemMedChem. 2009 Jan;4(1):41-4. doi: 10.1002/cmdc.200800313. ChemMedChem. 2009. PMID: 19058279 No abstract available.

5

From molecular shape to potent bioactive agents II: fragment-based de novo design.

Proschak E, Sander K, Zettl H, Tanrikulu Y, Rau O, Schneider P, Schubert-Zsilavecz M, Stark H, Schneider G. Proschak E, et al. ChemMedChem. 2009 Jan;4(1):45-8. doi: 10.1002/cmdc.200800314. ChemMedChem. 2009. PMID: 19058280 No abstract available.

6

Structure-based pharmacophore screening for natural-product-derived PPARgamma agonists.

Tanrikulu Y, Rau O, Schwarz O, Proschak E, Siems K, Müller-Kuhrt L, Schubert-Zsilavecz M, Schneider G. Tanrikulu Y, et al. Among authors: proschak e. Chembiochem. 2009 Jan 5;10(1):75-8. doi: 10.1002/cbic.200800520. Chembiochem. 2009. PMID: 19067454 No abstract available.

7

Nonacidic inhibitors of human microsomal prostaglandin synthase 1 (mPGES 1) identified by a multistep virtual screening protocol.

Rörsch F, Wobst I, Zettl H, Schubert-Zsilavecz M, Grösch S, Geisslinger G, Schneider G, Proschak E. Rörsch F, et al. Among authors: proschak e. J Med Chem. 2010 Jan 28;53(2):911-5. doi: 10.1021/jm9012505. J Med Chem. 2010. PMID: 20025212

8

Rational design of a pirinixic acid derivative that acts as subtype-selective PPARgamma modulator.

Thieme TM, Steri R, Proschak E, Paulke A, Schneider G, Schubert-Zsilavecz M. Thieme TM, et al. Among authors: proschak e. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2469-73. doi: 10.1016/j.bmcl.2010.03.008. Epub 2010 Mar 4. Bioorg Med Chem Lett. 2010. PMID: 20307981

9

Truxillic acid derivatives act as peroxisome proliferator-activated receptor gamma activators.

Steri R, Rupp M, Proschak E, Schroeter T, Zettl H, Hansen K, Schwarz O, Müller-Kuhrt L, Müller KR, Schneider G, Schubert-Zsilavecz M. Steri R, et al. Among authors: proschak e. Bioorg Med Chem Lett. 2010 May 1;20(9):2920-3. doi: 10.1016/j.bmcl.2010.03.026. Epub 2010 Mar 7. Bioorg Med Chem Lett. 2010. PMID: 20347594

10

Antidiabetic sulfonylureas modulate farnesoid X receptor activation and target gene transcription.

Steri R, Kara M, Proschak E, Steinhilber D, Schneider G, Schubert-Zsilavecz M. Steri R, et al. Among authors: proschak e. Future Med Chem. 2010 Apr;2(4):575-86. doi: 10.4155/fmc.10.10. Future Med Chem. 2010. PMID: 21426008

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