Liu CC - Search Results

1

Peripheral apoE4 enhances Alzheimer's pathology and impairs cognition by compromising cerebrovascular function.

Liu CC, Zhao J, Fu Y, Inoue Y, Ren Y, Chen Y, Doss SV, Shue F, Jeevaratnam S, Bastea L, Wang N, Martens YA, Qiao W, Wang M, Zhao N, Jia L, Yamazaki Y, Yamazaki A, Rosenberg CL, Wang Z, Kong D, Li Z, Kuchenbecker LA, Trottier ZA, Felton L, Rogers J, Quicksall ZS, Linares C, Knight J, Chen Y, Kurti A, Kanekiyo T, Fryer JD, Asmann YW, Storz P, Wang X, Peng J, Zhang B, Kim BYS, Bu G. Liu CC, et al. Nat Neurosci. 2022 Aug;25(8):1020-1033. doi: 10.1038/s41593-022-01127-0. Epub 2022 Aug 1. Nat Neurosci. 2022. PMID: 35915180 Free PMC article.

2

Cooperative folding and ligand-binding properties of LRP6 beta-propeller domains.

Liu CC, Pearson C, Bu G. Liu CC, et al. J Biol Chem. 2009 May 29;284(22):15299-307. doi: 10.1074/jbc.M807285200. Epub 2009 Mar 31. J Biol Chem. 2009. PMID: 19339249 Free PMC article.

3

LRP6 overexpression defines a class of breast cancer subtype and is a target for therapy.

Liu CC, Prior J, Piwnica-Worms D, Bu G. Liu CC, et al. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5136-41. doi: 10.1073/pnas.0911220107. Epub 2010 Mar 1. Proc Natl Acad Sci U S A. 2010. PMID: 20194742 Free PMC article.

4

Heparan sulphate proteoglycan and the low-density lipoprotein receptor-related protein 1 constitute major pathways for neuronal amyloid-beta uptake.

Kanekiyo T, Zhang J, Liu Q, Liu CC, Zhang L, Bu G. Kanekiyo T, et al. Among authors: liu cc, liu q. J Neurosci. 2011 Feb 2;31(5):1644-51. doi: 10.1523/JNEUROSCI.5491-10.2011. J Neurosci. 2011. PMID: 21289173 Free PMC article.

5

LRP1 in brain vascular smooth muscle cells mediates local clearance of Alzheimer's amyloid-β.

Kanekiyo T, Liu CC, Shinohara M, Li J, Bu G. Kanekiyo T, et al. Among authors: liu cc. J Neurosci. 2012 Nov 14;32(46):16458-65. doi: 10.1523/JNEUROSCI.3987-12.2012. J Neurosci. 2012. PMID: 23152628 Free PMC article.

6

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy.

Liu CC, Liu CC, Kanekiyo T, Xu H, Bu G. Liu CC, et al. Nat Rev Neurol. 2013 Feb;9(2):106-18. doi: 10.1038/nrneurol.2012.263. Epub 2013 Jan 8. Nat Rev Neurol. 2013. PMID: 23296339 Free PMC article. Review.

7

Neuronal clearance of amyloid-β by endocytic receptor LRP1.

Kanekiyo T, Cirrito JR, Liu CC, Shinohara M, Li J, Schuler DR, Shinohara M, Holtzman DM, Bu G. Kanekiyo T, et al. Among authors: liu cc. J Neurosci. 2013 Dec 4;33(49):19276-83. doi: 10.1523/JNEUROSCI.3487-13.2013. J Neurosci. 2013. PMID: 24305823 Free PMC article.

8

Retinoic acid isomers facilitate apolipoprotein E production and lipidation in astrocytes through the retinoid X receptor/retinoic acid receptor pathway.

Zhao J, Fu Y, Liu CC, Shinohara M, Nielsen HM, Dong Q, Kanekiyo T, Bu G. Zhao J, et al. Among authors: liu cc. J Biol Chem. 2014 Apr 18;289(16):11282-11292. doi: 10.1074/jbc.M113.526095. Epub 2014 Mar 5. J Biol Chem. 2014. PMID: 24599963 Free PMC article.

9

Tyrosine-based signal mediates LRP6 receptor endocytosis and desensitization of Wnt/β-catenin pathway signaling.

Liu CC, Kanekiyo T, Roth B, Bu G. Liu CC, et al. J Biol Chem. 2014 Oct 3;289(40):27562-70. doi: 10.1074/jbc.M113.533927. Epub 2014 Aug 20. J Biol Chem. 2014. PMID: 25143377 Free PMC article.

10

Deficiency in LRP6-mediated Wnt signaling contributes to synaptic abnormalities and amyloid pathology in Alzheimer's disease.

Liu CC, Tsai CW, Deak F, Rogers J, Penuliar M, Sung YM, Maher JN, Fu Y, Li X, Xu H, Estus S, Hoe HS, Fryer JD, Kanekiyo T, Bu G. Liu CC, et al. Neuron. 2014 Oct 1;84(1):63-77. doi: 10.1016/j.neuron.2014.08.048. Epub 2014 Sep 18. Neuron. 2014. PMID: 25242217 Free PMC article.

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