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A novel cell line panel reveals non-genetic mediators of platinum resistance and phenotypic diversity in high grade serous ovarian cancer.
Hoare JI, Hockings H, Saxena J, Silva VL, Haughey MJ, Wood GE, Nicolini F, Mirza H, McNeish IA, Huang W, Maniati E, Graham TA, Lockley M. Hoare JI, et al. Among authors: maniati e. Gynecol Oncol. 2022 Oct;167(1):96-106. doi: 10.1016/j.ygyno.2022.07.027. Epub 2022 Jul 30. Gynecol Oncol. 2022. PMID: 35918200 Free article.
A Strong B-cell Response Is Part of the Immune Landscape in Human High-Grade Serous Ovarian Metastases.
Montfort A, Pearce O, Maniati E, Vincent BG, Bixby L, Böhm S, Dowe T, Wilkes EH, Chakravarty P, Thompson R, Topping J, Cutillas PR, Lockley M, Serody JS, Capasso M, Balkwill FR. Montfort A, et al. Among authors: maniati e. Clin Cancer Res. 2017 Jan 1;23(1):250-262. doi: 10.1158/1078-0432.CCR-16-0081. Epub 2016 Jun 27. Clin Cancer Res. 2017. PMID: 27354470 Free PMC article.
Deconstruction of a Metastatic Tumor Microenvironment Reveals a Common Matrix Response in Human Cancers.
Pearce OMT, Delaine-Smith RM, Maniati E, Nichols S, Wang J, Böhm S, Rajeeve V, Ullah D, Chakravarty P, Jones RR, Montfort A, Dowe T, Gribben J, Jones JL, Kocher HM, Serody JS, Vincent BG, Connelly J, Brenton JD, Chelala C, Cutillas PR, Lockley M, Bessant C, Knight MM, Balkwill FR. Pearce OMT, et al. Among authors: maniati e. Cancer Discov. 2018 Mar;8(3):304-319. doi: 10.1158/2159-8290.CD-17-0284. Epub 2017 Dec 1. Cancer Discov. 2018. PMID: 29196464 Free PMC article.
A human multi-cellular model shows how platelets drive production of diseased extracellular matrix and tissue invasion.
Malacrida B, Nichols S, Maniati E, Jones R, Delanie-Smith R, Roozitalab R, Tyler EJ, Thomas M, Boot G, Mackerodt J, Lockley M, Knight MM, Balkwill FR, Pearce OMT. Malacrida B, et al. Among authors: maniati e. iScience. 2021 May 29;24(6):102676. doi: 10.1016/j.isci.2021.102676. eCollection 2021 Jun 25. iScience. 2021. PMID: 34189439 Free PMC article.
Immune Mechanisms of Resistance to Cediranib in Ovarian Cancer.
Gopinathan G, Berlato C, Lakhani A, Szabova L, Pegrum C, Pedrosa AR, Laforets F, Maniati E, Balkwill FR. Gopinathan G, et al. Among authors: maniati e. Mol Cancer Ther. 2022 Jun 1;21(6):1030-1043. doi: 10.1158/1535-7163.MCT-21-0689. Mol Cancer Ther. 2022. PMID: 35313341 Free PMC article.
Extracellular matrix educates an immunoregulatory tumor macrophage phenotype found in ovarian cancer metastasis.
Puttock EH, Tyler EJ, Manni M, Maniati E, Butterworth C, Burger Ramos M, Peerani E, Hirani P, Gauthier V, Liu Y, Maniscalco G, Rajeeve V, Cutillas P, Trevisan C, Pozzobon M, Lockley M, Rastrick J, Läubli H, White A, Pearce OMT. Puttock EH, et al. Among authors: maniati e. Nat Commun. 2023 May 15;14(1):2514. doi: 10.1038/s41467-023-38093-5. Nat Commun. 2023. PMID: 37188691 Free PMC article.
38 results