Hagemann TL - Search Results

1

Type II Alexander disease caused by splicing errors and aberrant overexpression of an uncharacterized GFAP isoform.

Helman G, Takanohashi A, Hagemann TL, Perng MD, Walkiewicz M, Woidill S, Sase S, Cross Z, Du Y, Zhao L, Waldman A, Haake BC, Fatemi A, Brenner M, Sherbini O, Messing A, Vanderver A, Simons C. Helman G, et al. Among authors: hagemann tl. Hum Mutat. 2022 Sep;43(9):1344. doi: 10.1002/humu.24400. Hum Mutat. 2022. PMID: 35920398 Free PMC article. No abstract available.

2

Gene expression analysis in mice with elevated glial fibrillary acidic protein and Rosenthal fibers reveals a stress response followed by glial activation and neuronal dysfunction.

Hagemann TL, Gaeta SA, Smith MA, Johnson DA, Johnson JA, Messing A. Hagemann TL, et al. Hum Mol Genet. 2005 Aug 15;14(16):2443-58. doi: 10.1093/hmg/ddi248. Epub 2005 Jul 13. Hum Mol Genet. 2005. PMID: 16014634

3

Alexander disease-associated glial fibrillary acidic protein mutations in mice induce Rosenthal fiber formation and a white matter stress response.

Hagemann TL, Connor JX, Messing A. Hagemann TL, et al. J Neurosci. 2006 Oct 25;26(43):11162-73. doi: 10.1523/JNEUROSCI.3260-06.2006. J Neurosci. 2006. PMID: 17065456 Free PMC article.

4

Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways.

Tang G, Yue Z, Talloczy Z, Hagemann T, Cho W, Messing A, Sulzer DL, Goldman JE. Tang G, et al. Hum Mol Genet. 2008 Jun 1;17(11):1540-55. doi: 10.1093/hmg/ddn042. Epub 2008 Feb 14. Hum Mol Genet. 2008. PMID: 18276609 Free PMC article.

5

Suppression of GFAP toxicity by alphaB-crystallin in mouse models of Alexander disease.

Hagemann TL, Boelens WC, Wawrousek EF, Messing A. Hagemann TL, et al. Hum Mol Genet. 2009 Apr 1;18(7):1190-9. doi: 10.1093/hmg/ddp013. Epub 2009 Jan 7. Hum Mol Genet. 2009. PMID: 19129171 Free PMC article.

6

Dual transgenic reporter mice as a tool for monitoring expression of glial fibrillary acidic protein.

Cho W, Hagemann TL, Johnson DA, Johnson JA, Messing A. Cho W, et al. Among authors: hagemann tl. J Neurochem. 2009 Jul;110(1):343-51. doi: 10.1111/j.1471-4159.2009.06146.x. Epub 2009 May 5. J Neurochem. 2009. PMID: 19457099 Free PMC article.

7

Alexander disease mutant glial fibrillary acidic protein compromises glutamate transport in astrocytes.

Tian R, Wu X, Hagemann TL, Sosunov AA, Messing A, McKhann GM, Goldman JE. Tian R, et al. Among authors: hagemann tl. J Neuropathol Exp Neurol. 2010 Apr;69(4):335-45. doi: 10.1097/NEN.0b013e3181d3cb52. J Neuropathol Exp Neurol. 2010. PMID: 20448479 Free PMC article.

8

Strategies for treatment in Alexander disease.

Messing A, LaPash Daniels CM, Hagemann TL. Messing A, et al. Among authors: hagemann tl. Neurotherapeutics. 2010 Oct;7(4):507-15. doi: 10.1016/j.nurt.2010.05.013. Neurotherapeutics. 2010. PMID: 20880512 Free PMC article. Review.

9

Genetic ablation of Nrf2/antioxidant response pathway in Alexander disease mice reduces hippocampal gliosis but does not impact survival.

Hagemann TL, Jobe EM, Messing A. Hagemann TL, et al. PLoS One. 2012;7(5):e37304. doi: 10.1371/journal.pone.0037304. Epub 2012 May 31. PLoS One. 2012. PMID: 22693571 Free PMC article.

10

Beneficial effects of Nrf2 overexpression in a mouse model of Alexander disease.

LaPash Daniels CM, Austin EV, Rockney DE, Jacka EM, Hagemann TL, Johnson DA, Johnson JA, Messing A. LaPash Daniels CM, et al. Among authors: hagemann tl. J Neurosci. 2012 Aug 1;32(31):10507-15. doi: 10.1523/JNEUROSCI.1494-12.2012. J Neurosci. 2012. PMID: 22855800 Free PMC article.

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