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DKK1 drives immune suppressive phenotypes in intrahepatic cholangiocarcinoma and can be targeted with anti-DKK1 therapeutic DKN-01.
Jarman EJ, Horcas-Lopez M, Waddell SH, MacMaster S, Gournopanos K, Soong DYH, Musialik KI, Tsokkou P, Ng ME, Cambridge WA, Wilson DH, Kagey MH, Newman W, Pollard JW, Boulter L. Jarman EJ, et al. Among authors: horcas lopez m. Liver Int. 2023 Jan;43(1):208-220. doi: 10.1111/liv.15383. Epub 2022 Sep 15. Liver Int. 2023. PMID: 35924447 Free PMC article.
Human iPS derived progenitors bioengineered into liver organoids using an inverted colloidal crystal poly (ethylene glycol) scaffold.
Ng SS, Saeb-Parsy K, Blackford SJI, Segal JM, Serra MP, Horcas-Lopez M, No DY, Mastoridis S, Jassem W, Frank CW, Cho NJ, Nakauchi H, Glenn JS, Rashid ST. Ng SS, et al. Among authors: horcas lopez m. Biomaterials. 2018 Nov;182:299-311. doi: 10.1016/j.biomaterials.2018.07.043. Epub 2018 Jul 27. Biomaterials. 2018. PMID: 30149262 Free PMC article.