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Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers.
Van Nyen T, Planque M, van Wagensveld L, Duarte JAG, Zaal EA, Talebi A, Rossi M, Körner PR, Rizzotto L, Moens S, De Wispelaere W, Baiden-Amissah REM, Sonke GS, Horlings HM, Eelen G, Berardi E, Swinnen JV, Berkers CR, Carmeliet P, Lambrechts D, Davidson B, Agami R, Fendt SM, Annibali D, Amant F. Van Nyen T, et al. Among authors: berkers cr. Nat Commun. 2022 Aug 5;13(1):4578. doi: 10.1038/s41467-022-32272-6. Nat Commun. 2022. PMID: 35931688 Free PMC article.
Thermal profiling reveals phenylalanine hydroxylase as an off-target of panobinostat.
Becher I, Werner T, Doce C, Zaal EA, Tögel I, Khan CA, Rueger A, Muelbaier M, Salzer E, Berkers CR, Fitzpatrick PF, Bantscheff M, Savitski MM. Becher I, et al. Among authors: berkers cr. Nat Chem Biol. 2016 Nov;12(11):908-910. doi: 10.1038/nchembio.2185. Epub 2016 Sep 26. Nat Chem Biol. 2016. PMID: 27669419
Multi-OMIC profiling of survival and metabolic signaling networks in cells subjected to photodynamic therapy.
Weijer R, Clavier S, Zaal EA, Pijls MM, van Kooten RT, Vermaas K, Leen R, Jongejan A, Moerland PD, van Kampen AH, van Kuilenburg AB, Berkers CR, Lemeer S, Heger M. Weijer R, et al. Among authors: berkers cr. Cell Mol Life Sci. 2017 Mar;74(6):1133-1151. doi: 10.1007/s00018-016-2401-0. Epub 2016 Nov 1. Cell Mol Life Sci. 2017. PMID: 27803950 Free PMC article.
TGFβ1-induced leucine limitation uncovered by differential ribosome codon reading.
Loayza-Puch F, Rooijers K, Zijlstra J, Moumbeini B, Zaal EA, Oude Vrielink JF, Lopes R, Ugalde AP, Berkers CR, Agami R. Loayza-Puch F, et al. Among authors: berkers cr. EMBO Rep. 2017 Apr;18(4):549-557. doi: 10.15252/embr.201744000. Epub 2017 Mar 8. EMBO Rep. 2017. PMID: 28274951 Free PMC article.
Proteasome Activation by Small Molecules.
Leestemaker Y, de Jong A, Witting KF, Penning R, Schuurman K, Rodenko B, Zaal EA, van de Kooij B, Laufer S, Heck AJR, Borst J, Scheper W, Berkers CR, Ovaa H. Leestemaker Y, et al. Among authors: berkers cr. Cell Chem Biol. 2017 Jun 22;24(6):725-736.e7. doi: 10.1016/j.chembiol.2017.05.010. Epub 2017 May 25. Cell Chem Biol. 2017. PMID: 28552582 Free article.
Proteomic and Metabolomic Analyses of Vanishing White Matter Mouse Astrocytes Reveal Deregulation of ER Functions.
Wisse LE, Penning R, Zaal EA, van Berkel CGM, Ter Braak TJ, Polder E, Kenney JW, Proud CG, Berkers CR, Altelaar MAF, Speijer D, van der Knaap MS, Abbink TEM. Wisse LE, et al. Among authors: berkers cr. Front Cell Neurosci. 2017 Dec 20;11:411. doi: 10.3389/fncel.2017.00411. eCollection 2017. Front Cell Neurosci. 2017. PMID: 29375313 Free PMC article.
75 results