Mori M - Search Results

1

Novel pyrazolo[3,4-d]pyrimidines as dual Src/Bcr-Abl kinase inhibitors: Synthesis and biological evaluation for chronic myeloid leukemia treatment.

Di Maria S, Picarazzi F, Mori M, Cianciusi A, Carbone A, Crespan E, Perini C, Sabetta S, Deplano S, Poggialini F, Molinari A, Aronne R, Maccioni E, Maga G, Angelucci A, Schenone S, Musumeci F, Dreassi E. Di Maria S, et al. Among authors: mori m. Bioorg Chem. 2022 Nov;128:106071. doi: 10.1016/j.bioorg.2022.106071. Epub 2022 Aug 1. Bioorg Chem. 2022. PMID: 35932498

2

2-Hydroxypropyl-β-cyclodextrin strongly improves water solubility and anti-proliferative activity of pyrazolo[3,4-d]pyrimidines Src-Abl dual inhibitors.

Dreassi E, Zizzari AT, Mori M, Filippi I, Belfiore A, Naldini A, Carraro F, Santucci A, Schenone S, Botta M. Dreassi E, et al. Among authors: mori m. Eur J Med Chem. 2010 Dec;45(12):5958-64. doi: 10.1016/j.ejmech.2010.09.062. Epub 2010 Oct 8. Eur J Med Chem. 2010. PMID: 20970221

3

Computational techniques are valuable tools for the discovery of protein-protein interaction inhibitors: the 14-3-3σ case.

Corradi V, Mancini M, Santucci MA, Carlomagno T, Sanfelice D, Mori M, Vignaroli G, Falchi F, Manetti F, Radi M, Botta M. Corradi V, et al. Among authors: mori m. Bioorg Med Chem Lett. 2011 Nov 15;21(22):6867-71. doi: 10.1016/j.bmcl.2011.09.011. Epub 2011 Sep 10. Bioorg Med Chem Lett. 2011. PMID: 21962576

4

A combination strategy to inhibit Pim-1: synergism between noncompetitive and ATP-competitive inhibitors.

Mori M, Tintori C, Christopher RS, Radi M, Schenone S, Musumeci F, Brullo C, Sanità P, Delle Monache S, Angelucci A, Kissova M, Crespan E, Maga G, Botta M. Mori M, et al. ChemMedChem. 2013 Mar;8(3):484-96. doi: 10.1002/cmdc.201200480. ChemMedChem. 2013. PMID: 23436791

5

Differentially activated Src kinase in chemo-naïve human primary osteosarcoma cells and effects of a Src kinase inhibitor.

Laschi M, Bernardini G, Geminiani M, Manetti F, Mori M, Spreafico A, Campanacci D, Capanna R, Schenone S, Botta M, Santucci A. Laschi M, et al. Among authors: mori m. Biofactors. 2017 Nov;43(6):801-811. doi: 10.1002/biof.1382. Epub 2017 Aug 8. Biofactors. 2017. PMID: 28786551

6

Potent and Selective Carboxylic Acid Inhibitors of Tumor-Associated Carbonic Anhydrases IX and XII.

Cau Y, Vullo D, Mori M, Dreassi E, Supuran CT, Botta M. Cau Y, et al. Among authors: mori m. Molecules. 2017 Dec 22;23(1):17. doi: 10.3390/molecules23010017. Molecules. 2017. PMID: 29271882 Free PMC article.

7

Design, synthesis, SAR and biological investigation of 3-(carboxymethyl)rhodanine and aminothiazole inhibitors of Mycobacterium tuberculosis Zmp1.

Mori M, Deodato D, Kasula M, Ferraris DM, Sanna A, De Logu A, Rizzi M, Botta M. Mori M, et al. Bioorg Med Chem Lett. 2018 Feb 15;28(4):637-641. doi: 10.1016/j.bmcl.2018.01.031. Epub 2018 Jan 31. Bioorg Med Chem Lett. 2018. PMID: 29395975

8

Current trends in Hedgehog signaling pathway inhibition by small molecules.

Ghirga F, Mori M, Infante P. Ghirga F, et al. Among authors: mori m. Bioorg Med Chem Lett. 2018 Oct 15;28(19):3131-3140. doi: 10.1016/j.bmcl.2018.08.033. Epub 2018 Aug 27. Bioorg Med Chem Lett. 2018. PMID: 30177379 Review.

9

Synthetic thiosemicarbazones as a new class of Mycobacterium tuberculosis protein tyrosine phosphatase A inhibitors.

Sens L, de Souza ACA, Pacheco LA, Menegatti ACO, Mori M, Mascarello A, Nunes RJ, Terenzi H. Sens L, et al. Among authors: mori m. Bioorg Med Chem. 2018 Nov 15;26(21):5742-5750. doi: 10.1016/j.bmc.2018.10.030. Epub 2018 Oct 27. Bioorg Med Chem. 2018. PMID: 30389409 Free article.

10

Chemically stable inhibitors of 14-3-3 protein-protein interactions derived from BV02.

Iralde-Lorente L, Cau Y, Clementi L, Franci L, Tassone G, Valensin D, Mori M, Angelucci A, Chiariello M, Botta M. Iralde-Lorente L, et al. Among authors: mori m. J Enzyme Inhib Med Chem. 2019 Dec;34(1):657-664. doi: 10.1080/14756366.2019.1574779. J Enzyme Inhib Med Chem. 2019. PMID: 30727786 Free PMC article.

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