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Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development.
McCall CM, Miliani de Marval PL, Chastain PD 2nd, Jackson SC, He YJ, Kotake Y, Cook JG, Xiong Y. McCall CM, et al. Among authors: xiong y. Mol Cell Biol. 2008 Sep;28(18):5621-33. doi: 10.1128/MCB.00232-08. Epub 2008 Jul 7. Mol Cell Biol. 2008. PMID: 18606781 Free PMC article.
CRL4s: the CUL4-RING E3 ubiquitin ligases.
Jackson S, Xiong Y. Jackson S, et al. Among authors: xiong y. Trends Biochem Sci. 2009 Nov;34(11):562-70. doi: 10.1016/j.tibs.2009.07.002. Epub 2009 Oct 7. Trends Biochem Sci. 2009. PMID: 19818632 Free PMC article. Review.
The 3M complex maintains microtubule and genome integrity.
Yan J, Yan F, Li Z, Sinnott B, Cappell KM, Yu Y, Mo J, Duncan JA, Chen X, Cormier-Daire V, Whitehurst AW, Xiong Y. Yan J, et al. Among authors: xiong y. Mol Cell. 2014 Jun 5;54(5):791-804. doi: 10.1016/j.molcel.2014.03.047. Epub 2014 May 1. Mol Cell. 2014. PMID: 24793695 Free PMC article.
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