Plückthun A - Search Results

1

Programmable DARPin-based receptors for the detection of thrombotic markers.

Strittmatter T, Wang Y, Bertschi A, Scheller L, Freitag PC, Ray PG, Stuecheli P, Schaefer JV, Reinberg T, Tsakiris D, Plückthun A, Ye H, Fussenegger M. Strittmatter T, et al. Among authors: pluckthun a. Nat Chem Biol. 2022 Oct;18(10):1125-1134. doi: 10.1038/s41589-022-01095-3. Epub 2022 Aug 8. Nat Chem Biol. 2022. PMID: 35941237 Free PMC article.

2

In vitro selection and characterization of DARPins and Fab fragments for the co-crystallization of membrane proteins: The Na(+)-citrate symporter CitS as an example.

Huber T, Steiner D, Röthlisberger D, Plückthun A. Huber T, et al. Among authors: pluckthun a. J Struct Biol. 2007 Aug;159(2):206-21. doi: 10.1016/j.jsb.2007.01.013. Epub 2007 Feb 3. J Struct Biol. 2007. PMID: 17369048

3

Stabilizing ionic interactions in a full-consensus ankyrin repeat protein.

Merz T, Wetzel SK, Firbank S, Plückthun A, Grütter MG, Mittl PR. Merz T, et al. Among authors: pluckthun a. J Mol Biol. 2008 Feb 8;376(1):232-40. doi: 10.1016/j.jmb.2007.11.047. Epub 2007 Nov 22. J Mol Biol. 2008. PMID: 18155045

4

Efficient selection of DARPins with sub-nanomolar affinities using SRP phage display.

Steiner D, Forrer P, Plückthun A. Steiner D, et al. Among authors: pluckthun a. J Mol Biol. 2008 Oct 24;382(5):1211-27. doi: 10.1016/j.jmb.2008.07.085. Epub 2008 Aug 6. J Mol Biol. 2008. PMID: 18706916 Free article.

5

Residue-resolved stability of full-consensus ankyrin repeat proteins probed by NMR.

Wetzel SK, Ewald C, Settanni G, Jurt S, Plückthun A, Zerbe O. Wetzel SK, et al. Among authors: pluckthun a. J Mol Biol. 2010 Sep 10;402(1):241-58. doi: 10.1016/j.jmb.2010.07.031. Epub 2010 Jul 21. J Mol Biol. 2010. PMID: 20654623

6

Her2-specific multivalent adapters confer designed tropism to adenovirus for gene targeting.

Dreier B, Mikheeva G, Belousova N, Parizek P, Boczek E, Jelesarov I, Forrer P, Plückthun A, Krasnykh V. Dreier B, et al. Among authors: pluckthun a. J Mol Biol. 2011 Jan 14;405(2):410-26. doi: 10.1016/j.jmb.2010.10.040. Epub 2010 Nov 5. J Mol Biol. 2011. PMID: 21056576 Free PMC article.

7

Engineering aggregation resistance in IgG by two independent mechanisms: lessons from comparison of Pichia pastoris and mammalian cell expression.

Schaefer JV, Plückthun A. Schaefer JV, et al. Among authors: pluckthun a. J Mol Biol. 2012 Apr 6;417(4):309-35. doi: 10.1016/j.jmb.2012.01.027. Epub 2012 Jan 27. J Mol Biol. 2012. PMID: 22306407

8

Designed ankyrin repeat proteins (DARPins) as novel isoform-specific intracellular inhibitors of c-Jun N-terminal kinases.

Parizek P, Kummer L, Rube P, Prinz A, Herberg FW, Plückthun A. Parizek P, et al. Among authors: pluckthun a. ACS Chem Biol. 2012 Aug 17;7(8):1356-66. doi: 10.1021/cb3001167. Epub 2012 May 25. ACS Chem Biol. 2012. PMID: 22568706

9

Transfer of engineered biophysical properties between different antibody formats and expression systems.

Schaefer JV, Plückthun A. Schaefer JV, et al. Among authors: pluckthun a. Protein Eng Des Sel. 2012 Oct;25(10):485-506. doi: 10.1093/protein/gzs039. Epub 2012 Jul 4. Protein Eng Des Sel. 2012. PMID: 22763265

10

Development of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adapters.

Dreier B, Honegger A, Hess C, Nagy-Davidescu G, Mittl PR, Grütter MG, Belousova N, Mikheeva G, Krasnykh V, Plückthun A. Dreier B, et al. Among authors: pluckthun a. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):E869-77. doi: 10.1073/pnas.1213653110. Epub 2013 Feb 19. Proc Natl Acad Sci U S A. 2013. PMID: 23431166 Free PMC article.

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