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Rapid evolution and host immunity drive the rise and fall of carbapenem resistance during an acute Pseudomonas aeruginosa infection.
Wheatley R, Diaz Caballero J, Kapel N, de Winter FHR, Jangir P, Quinn A, Del Barrio-Tofiño E, López-Causapé C, Hedge J, Torrens G, Van der Schalk T, Xavier BB, Fernández-Cuenca F, Arenzana A, Recanatini C, Timbermont L, Sifakis F, Ruzin A, Ali O, Lammens C, Goossens H, Kluytmans J, Kumar-Singh S, Oliver A, Malhotra-Kumar S, MacLean C. Wheatley R, et al. Nat Commun. 2021 Apr 28;12(1):2460. doi: 10.1038/s41467-021-22814-9. Nat Commun. 2021. PMID: 33911082 Free PMC article.
Gut to lung translocation and antibiotic mediated selection shape the dynamics of Pseudomonas aeruginosa in an ICU patient.
Wheatley RM, Caballero JD, van der Schalk TE, De Winter FHR, Shaw LP, Kapel N, Recanatini C, Timbermont L, Kluytmans J, Esser M, Lacoma A, Prat-Aymerich C, Oliver A, Kumar-Singh S, Malhotra-Kumar S, Craig MacLean R. Wheatley RM, et al. Nat Commun. 2022 Nov 22;13(1):6523. doi: 10.1038/s41467-022-34101-2. Nat Commun. 2022. PMID: 36414617 Free PMC article.
Mixed strain pathogen populations accelerate the evolution of antibiotic resistance in patients.
Diaz Caballero J, Wheatley RM, Kapel N, López-Causapé C, Van der Schalk T, Quinn A, Shaw LP, Ogunlana L, Recanatini C, Xavier BB, Timbermont L, Kluytmans J, Ruzin A, Esser M, Malhotra-Kumar S, Oliver A, MacLean RC. Diaz Caballero J, et al. Among authors: wheatley rm. Nat Commun. 2023 Jul 12;14(1):4083. doi: 10.1038/s41467-023-39416-2. Nat Commun. 2023. PMID: 37438338 Free PMC article.
Fitness costs of CRISPR-Cas systems in bacteria.
Zaayman M, Wheatley RM. Zaayman M, et al. Microbiology (Reading). 2022 Jul;168(7). doi: 10.1099/mic.0.001209. Microbiology (Reading). 2022. PMID: 35849532 Free article. Review.
166 results