Ji X - Search Results

1

Discovery of novel 1,2,4-triazole phenylalanine derivatives targeting an unexplored region within the interprotomer pocket of the HIV capsid protein.

Jiang X, Sharma PP, Rathi B, Ji X, Hu L, Gao Z, Kang D, Wang Z, Xie M, Xu S, Zhang X, De Clercq E, Cocklin S, Pannecouque C, Dick A, Liu X, Zhan P. Jiang X, et al. Among authors: ji x. J Med Virol. 2022 Dec;94(12):5975-5986. doi: 10.1002/jmv.28064. Epub 2022 Aug 18. J Med Virol. 2022. PMID: 35949003 Free PMC article.

2

Design, synthesis, and antiviral activity of phenylalanine derivatives as HIV-1 capsid inhibitors.

Li J, Jiang X, Dick A, Prakash Sharma P, Chen CH, Rathi B, Kang D, Wang Z, Ji X, Lee KH, Cocklin S, Liu X, Zhan P. Li J, et al. Among authors: ji x. Bioorg Med Chem. 2021 Oct 15;48:116414. doi: 10.1016/j.bmc.2021.116414. Epub 2021 Sep 17. Bioorg Med Chem. 2021. PMID: 34562701 Free PMC article.

3

Design, Synthesis, and Evaluation of a Set of Carboxylic Acid and Phosphate Prodrugs Derived from HBV Capsid Protein Allosteric Modulator NVR 3-778.

Ji X, Jiang X, Kobayashi C, Ren Y, Hu L, Gao Z, Kang D, Jia R, Zhang X, Zhao S, Watashi K, Liu X, Zhan P. Ji X, et al. Molecules. 2022 Sep 14;27(18):5987. doi: 10.3390/molecules27185987. Molecules. 2022. PMID: 36144715 Free PMC article.

4

Design, Synthesis and Structure-Activity Relationships of Phenylalanine-Containing Peptidomimetics as Novel HIV-1 Capsid Binders Based on Ugi Four-Component Reaction.

Ji X, Li J, Sharma PP, Jiang X, Rathi B, Gao Z, Hu L, Kang D, De Clercq E, Cocklin S, Liu C, Pannecouque C, Dick A, Liu X, Zhan P. Ji X, et al. Molecules. 2022 Sep 14;27(18):5995. doi: 10.3390/molecules27185995. Molecules. 2022. PMID: 36144727 Free PMC article.

5

Discovery of Novel Boron-Containing N-Substituted Oseltamivir Derivatives as Anti-Influenza A Virus Agents for Overcoming N1-H274Y Oseltamivir-Resistant.

Jia R, Zhang J, Zhang J, Bertagnin C, Bonomini A, Guizzo L, Gao Z, Ji X, Li Z, Liu C, Ju H, Ma X, Loregian A, Huang B, Zhan P, Liu X. Jia R, et al. Among authors: ji x. Molecules. 2022 Sep 29;27(19):6426. doi: 10.3390/molecules27196426. Molecules. 2022. PMID: 36234966 Free PMC article.

6

Discovery of diarylpyrimidine derivatives bearing piperazine sulfonyl as potent HIV-1 nonnucleoside reverse transcriptase inhibitors.

Jiang X, Huang B, Rumrill S, Pople D, Zalloum WA, Kang D, Zhao F, Ji X, Gao Z, Hu L, Wang Z, Xie M, De Clercq E, Ruiz FX, Arnold E, Pannecouque C, Liu X, Zhan P. Jiang X, et al. Among authors: ji x. Commun Chem. 2023 Apr 29;6(1):83. doi: 10.1038/s42004-023-00888-4. Commun Chem. 2023. PMID: 37120482 Free PMC article.

7

Discovery of novel diarypyrimidine derivatives bearing six-membered non-aromatic heterocycles as potent HIV-1 NNRTIs with improved anti-resistance and drug-like profiles.

Jiang X, Huang B, Zalloum WA, Chen CH, Ji X, Gao Z, Dai J, Xie M, Kang D, De Clercq E, Pannecouque C, Liu X, Zhan P. Jiang X, et al. Among authors: ji x. Eur J Med Chem. 2023 Oct 5;258:115605. doi: 10.1016/j.ejmech.2023.115605. Epub 2023 Jun 28. Eur J Med Chem. 2023. PMID: 37393790

8

Discovery of low-molecular-weight phenylalanine derivatives as novel HIV capsid modulators with improved antiretroviral activity and metabolic stability.

Jiang X, Gao Z, Sharma PP, Kumar S, Rathi B, Ji X, Dai J, Xie M, Dong G, Xu S, De Clercq E, Pannecouque C, Dick A, Zhan P, Liu X. Jiang X, et al. Among authors: ji x. J Med Virol. 2024 Apr;96(4):e29594. doi: 10.1002/jmv.29594. J Med Virol. 2024. PMID: 38576317

9

Identification of novel diarylpyrimidine derivatives as potent HIV-1 non-nucleoside reverse transcriptase inhibitors against wild-type and K103N mutant viruses.

Jiang X, Zalloum WA, Gao Z, Dai J, Ji X, Xie M, Dong G, De Clercq E, Huang B, Pannecouque C, Zhan P, Liu X. Jiang X, et al. Among authors: ji x. Eur J Med Chem. 2024 Dec 15;280:116941. doi: 10.1016/j.ejmech.2024.116941. Epub 2024 Oct 5. Eur J Med Chem. 2024. PMID: 39369484

10

Visualization of Mechanical Force Regulation of Exosome Secretion Using High Time-Spatial Resolution Imaging.

Ji X, Zhang J, Qiu Y, Shi Y, Shao L, Wang H, Gao J, Cai M, Pan Y, Xu H, Wang H. Ji X, et al. Anal Chem. 2025 Jan 6. doi: 10.1021/acs.analchem.4c04690. Online ahead of print. Anal Chem. 2025. PMID: 39760310

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