Saville KM - Search Results

1

Live Cell Detection of Poly(ADP-Ribose) for Use in Genetic and Genotoxic Compound Screens.

Koczor CA, Haider AJ, Saville KM, Li J, Andrews JF, Beiser AV, Sobol RW. Koczor CA, et al. Among authors: saville km. Cancers (Basel). 2022 Jul 28;14(15):3676. doi: 10.3390/cancers14153676. Cancers (Basel). 2022. PMID: 35954352 Free PMC article.

2

NAD⁺-mediated regulation of mammalian base excision repair.

Saville KM, Clark J, Wilk A, Rogers GD, Andrews JF, Koczor CA, Sobol RW. Saville KM, et al. DNA Repair (Amst). 2020 Sep;93:102930. doi: 10.1016/j.dnarep.2020.102930. DNA Repair (Amst). 2020. PMID: 33087267 Free PMC article. Review.

3

Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD⁺/SIRT6 axis.

Koczor CA, Saville KM, Andrews JF, Clark J, Fang Q, Li J, Al-Rahahleh RQ, Ibrahim M, McClellan S, Makarov MV, Migaud ME, Sobol RW. Koczor CA, et al. Among authors: saville km. Cell Rep. 2021 Nov 2;37(5):109917. doi: 10.1016/j.celrep.2021.109917. Cell Rep. 2021. PMID: 34731617 Free PMC article.

4

Overcoming Temozolomide Resistance in Glioblastoma via Enhanced NAD⁺ Bioavailability and Inhibition of Poly-ADP-Ribose Glycohydrolase.

Li J, Koczor CA, Saville KM, Hayat F, Beiser A, McClellan S, Migaud ME, Sobol RW. Li J, et al. Among authors: saville km. Cancers (Basel). 2022 Jul 22;14(15):3572. doi: 10.3390/cancers14153572. Cancers (Basel). 2022. PMID: 35892832 Free PMC article.

5

Quantitative Analysis of Nuclear Poly(ADP-Ribose) Dynamics in Response to Laser-Induced DNA Damage.

Koczor CA, Saville KM, Al-Rahahleh RQ, Andrews JF, Li J, Sobol RW. Koczor CA, et al. Among authors: saville km. Methods Mol Biol. 2023;2609:43-59. doi: 10.1007/978-1-0716-2891-1_3. Methods Mol Biol. 2023. PMID: 36515828 Free PMC article.

6

Overexpression of the WWE domain of RNF146 modulates poly-(ADP)-ribose dynamics at sites of DNA damage.

Al-Rahahleh RQ, Saville KM, Andrews JF, Wu Z, Koczor CA, Sobol RW. Al-Rahahleh RQ, et al. Among authors: saville km. bioRxiv [Preprint]. 2023 Dec 29:2023.12.29.573650. doi: 10.1101/2023.12.29.573650. bioRxiv. 2023. PMID: 38234836 Free PMC article. Preprint.

7

Oncometabolite 2-hydroxyglutarate suppresses basal protein levels of DNA polymerase beta that enhances alkylating agent and PARG inhibition induced cytotoxicity.

Saville KM, Al-Rahahleh RQ, Siddiqui AH, Andrews ME, Roos WP, Koczor CA, Andrews JF, Hayat F, Migaud ME, Sobol RW. Saville KM, et al. DNA Repair (Amst). 2024 Aug;140:103700. doi: 10.1016/j.dnarep.2024.103700. Epub 2024 Jun 4. DNA Repair (Amst). 2024. PMID: 38897003 Free article.

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