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Increasing cell size remodels the proteome and promotes senescence.
Lanz MC, Zatulovskiy E, Swaffer MP, Zhang L, Ilerten I, Zhang S, You DS, Marinov G, McAlpine P, Elias JE, Skotheim JM. Lanz MC, et al. Mol Cell. 2022 Sep 1;82(17):3255-3269.e8. doi: 10.1016/j.molcel.2022.07.017. Epub 2022 Aug 19. Mol Cell. 2022. PMID: 35987199 Free PMC article.
Whi5 is diluted and protein synthesis does not dramatically increase in pre-Start G1.
Schmoller KM, Lanz MC, Kim J, Koivomagi M, Qu Y, Tang C, Kukhtevich IV, Schneider R, Rudolf F, Moreno DF, Aldea M, Lucena R, Skotheim JM. Schmoller KM, et al. Among authors: lanz mc. Mol Biol Cell. 2022 May 1;33(5):lt1. doi: 10.1091/mbc.E21-01-0029. Mol Biol Cell. 2022. PMID: 35482510 Free PMC article. No abstract available.
Delineation of proteome changes driven by cell size and growth rate.
Zatulovskiy E, Lanz MC, Zhang S, McCarthy F, Elias JE, Skotheim JM. Zatulovskiy E, et al. Among authors: lanz mc. Front Cell Dev Biol. 2022 Sep 5;10:980721. doi: 10.3389/fcell.2022.980721. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36133920 Free PMC article.
Genome dilution by cell growth drives starvation-like proteome remodeling in mammalian and yeast cells.
Lanz MC, Zhang S, Swaffer MP, Hernández Götz L, McCarty F, Ziv I, Jarosz DF, Elias JE, Skotheim JM. Lanz MC, et al. bioRxiv [Preprint]. 2023 Oct 26:2023.10.16.562558. doi: 10.1101/2023.10.16.562558. bioRxiv. 2023. Update in: Nat Struct Mol Biol. 2024 Dec;31(12):1859-1871. doi: 10.1038/s41594-024-01353-z PMID: 37905015 Free PMC article. Updated. Preprint.
Checkpoint-mediated DNA polymerase ε exonuclease activity curbing counteracts resection-driven fork collapse.
Pellicanò G, Al Mamun M, Jurado-Santiago D, Villa-Hernández S, Yin X, Giannattasio M, Lanz MC, Smolka MB, Yeeles J, Shirahige K, García-Díaz M, Bermejo R. Pellicanò G, et al. Among authors: lanz mc. Mol Cell. 2021 Jul 1;81(13):2778-2792.e4. doi: 10.1016/j.molcel.2021.04.006. Epub 2021 Apr 30. Mol Cell. 2021. PMID: 33932350 Free PMC article.
19 results