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Page 1
Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing.
Kessler N, Viehmann SF, Krollmann C, Mai K, Kirschner KM, Luksch H, Kotagiri P, Böhner AMC, Huugen D, de Oliveira Mann CC, Otten S, Weiss SAI, Zillinger T, Dobrikova K, Jenne DE, Behrendt R, Ablasser A, Bartok E, Hartmann G, Hopfner KP, Lyons PA, Boor P, Rösen-Wolff A, Teichmann LL, Heeringa P, Kurts C, Garbi N. Kessler N, et al. Among authors: de oliveira mann cc. J Exp Med. 2022 Oct 3;219(10):e20220759. doi: 10.1084/jem.20220759. Epub 2022 Aug 23. J Exp Med. 2022. PMID: 35997679 Free PMC article.
Structural mechanism of cytosolic DNA sensing by cGAS.
Civril F, Deimling T, de Oliveira Mann CC, Ablasser A, Moldt M, Witte G, Hornung V, Hopfner KP. Civril F, et al. Among authors: de oliveira mann cc. Nature. 2013 Jun 20;498(7454):332-7. doi: 10.1038/nature12305. Epub 2013 May 30. Nature. 2013. PMID: 23722159 Free PMC article.
cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders.
Andreeva L, Hiller B, Kostrewa D, Lässig C, de Oliveira Mann CC, Jan Drexler D, Maiser A, Gaidt M, Leonhardt H, Hornung V, Hopfner KP. Andreeva L, et al. Among authors: de oliveira mann cc. Nature. 2017 Sep 21;549(7672):394-398. doi: 10.1038/nature23890. Epub 2017 Sep 13. Nature. 2017. PMID: 28902841
Structural basis for sequestration and autoinhibition of cGAS by chromatin.
Michalski S, de Oliveira Mann CC, Stafford CA, Witte G, Bartho J, Lammens K, Hornung V, Hopfner KP. Michalski S, et al. Among authors: de oliveira mann cc. Nature. 2020 Nov;587(7835):678-682. doi: 10.1038/s41586-020-2748-0. Epub 2020 Sep 10. Nature. 2020. PMID: 32911480
Nuclear cGAS: guard or prisoner?
de Oliveira Mann CC, Hopfner KP. de Oliveira Mann CC, et al. EMBO J. 2021 Aug 16;40(16):e108293. doi: 10.15252/embj.2021108293. Epub 2021 Jul 12. EMBO J. 2021. PMID: 34250619 Free PMC article. Review.
Correction: Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing.
Kessler N, Viehmann SF, Krollmann C, Mai K, Kirschner KM, Luksch H, Kotagiri P, Böhner AMC, Huugen D, de Oliveira Mann CC, Otten S, Weiss SAI, Zillinger T, Dobrikova K, Jenne DE, Behrendt R, Ablasser A, Bartok E, Hartmann G, Hopfner KP, Lyons PA, Boor P, Rösen-Wolff A, Teichmann LL, Heeringa P, Kurts C, Garbi N. Kessler N, et al. Among authors: de oliveira mann cc. J Exp Med. 2022 Dec 5;219(12):e2022075911022022c. doi: 10.1084/jem.2022075911022022c. Epub 2022 Nov 11. J Exp Med. 2022. PMID: 36367753 Free PMC article. No abstract available.
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