Yan B - Search Results

1

Effect of alcohol exposure on the efficacy and safety of tenofovir alafenamide fumarate, a major medicine against human immunodeficiency virus.

Liu W, Yu S, Yan B. Liu W, et al. Among authors: yan b. Biochem Pharmacol. 2022 Oct;204:115224. doi: 10.1016/j.bcp.2022.115224. Epub 2022 Aug 22. Biochem Pharmacol. 2022. PMID: 36007574 Free PMC article.

2

Carboxylesterase-2 is a highly sensitive target of the antiobesity agent orlistat with profound implications in the activation of anticancer prodrugs.

Xiao D, Shi D, Yang D, Barthel B, Koch TH, Yan B. Xiao D, et al. Among authors: yan b. Biochem Pharmacol. 2013 Feb 1;85(3):439-47. doi: 10.1016/j.bcp.2012.11.026. Epub 2012 Dec 7. Biochem Pharmacol. 2013. PMID: 23228697 Free PMC article.

3

Remdesivir potently inhibits carboxylesterase-2 through covalent modifications: signifying strong drug-drug interactions.

Shen Y, Eades W, Yan B. Shen Y, et al. Among authors: yan b. Fundam Clin Pharmacol. 2021 Apr;35(2):432-434. doi: 10.1111/fcp.12643. Epub 2021 Jan 6. Fundam Clin Pharmacol. 2021. PMID: 33369768 Free PMC article.

4

The COVID-19 Oral Drug Molnupiravir Is a CES2 Substrate: Potential Drug-Drug Interactions and Impact of CES2 Genetic Polymorphism In Vitro.

Shen Y, Eades W, Liu W, Yan B. Shen Y, et al. Among authors: yan b. Drug Metab Dispos. 2022 Sep;50(9):1151-1160. doi: 10.1124/dmd.122.000918. Epub 2022 Jul 5. Drug Metab Dispos. 2022. PMID: 35790245 Free PMC article.

5

Viral target and metabolism-based rationale for combined use of recently authorized small molecule COVID-19 medicines: Molnupiravir, nirmatrelvir, and remdesivir.

Yan D, Yan B. Yan D, et al. Among authors: yan b. Fundam Clin Pharmacol. 2023 Aug;37(4):726-738. doi: 10.1111/fcp.12889. Epub 2023 Mar 25. Fundam Clin Pharmacol. 2023. PMID: 36931725 Free PMC article. Review.

6

Antiplatelet agents aspirin and clopidogrel are hydrolyzed by distinct carboxylesterases, and clopidogrel is transesterificated in the presence of ethyl alcohol.

Tang M, Mukundan M, Yang J, Charpentier N, LeCluyse EL, Black C, Yang D, Shi D, Yan B. Tang M, et al. Among authors: yan b. J Pharmacol Exp Ther. 2006 Dec;319(3):1467-76. doi: 10.1124/jpet.106.110577. Epub 2006 Aug 30. J Pharmacol Exp Ther. 2006. PMID: 16943252

7

Anti-influenza prodrug oseltamivir is activated by carboxylesterase human carboxylesterase 1, and the activation is inhibited by antiplatelet agent clopidogrel.

Shi D, Yang J, Yang D, LeCluyse EL, Black C, You L, Akhlaghi F, Yan B. Shi D, et al. Among authors: yan b. J Pharmacol Exp Ther. 2006 Dec;319(3):1477-84. doi: 10.1124/jpet.106.111807. Epub 2006 Sep 11. J Pharmacol Exp Ther. 2006. PMID: 16966469

8

Human carboxylesterases HCE1 and HCE2: ontogenic expression, inter-individual variability and differential hydrolysis of oseltamivir, aspirin, deltamethrin and permethrin.

Yang D, Pearce RE, Wang X, Gaedigk R, Wan YJ, Yan B. Yang D, et al. Among authors: yan b. Biochem Pharmacol. 2009 Jan 15;77(2):238-47. doi: 10.1016/j.bcp.2008.10.005. Epub 2008 Oct 15. Biochem Pharmacol. 2009. PMID: 18983829 Free PMC article.

9

Xiao D, Chen YT, Yang D, Yan B. Xiao D, et al. Among authors: yan b. Biochem Pharmacol. 2012 Jul 15;84(2):232-9. doi: 10.1016/j.bcp.2012.04.002. Epub 2012 Apr 10. Biochem Pharmacol. 2012. PMID: 22513142 Free PMC article.

10

Antioxidant sulforaphane and sensitizer trinitrobenzene sulfonate induce carboxylesterase-1 through a novel element transactivated by nuclear factor-E2 related factor-2.

Chen YT, Shi D, Yang D, Yan B. Chen YT, et al. Among authors: yan b. Biochem Pharmacol. 2012 Sep 15;84(6):864-71. doi: 10.1016/j.bcp.2012.06.025. Epub 2012 Jul 6. Biochem Pharmacol. 2012. PMID: 22776248 Free PMC article.

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