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In Silico Enabled Discovery of KAI-11101, a Preclinical DLK Inhibitor for the Treatment of Neurodegenerative Disease and Neuronal Injury.
Lagiakos HR, Zou Y, Igawa H, Therrien E, Lawrenz M, Kato M, Svensson M, Gray F, Jensen K, Dahlgren MK, Pelletier RD, Dingley K, Bell JA, Liu Z, Jiang Y, Zhou H, Skene RJ, Nie Z. Lagiakos HR, et al. Among authors: svensson m. J Med Chem. 2024 Dec 13. doi: 10.1021/acs.jmedchem.4c02074. Online ahead of print. J Med Chem. 2024. PMID: 39670820
Longitudinal serum bicarbonate and mortality risk in older patients with advanced chronic kidney disease: analyses from the EQUAL cohort.
Lombardi G, Chesnaye NC, Caskey FJ, Dekker FW, Evans M, Heimburger O, Pippias M, Torino C, Szymczak M, Drechsler C, Wanner C, Gambaro G, Stel VS, Jager KJ, Ferraro PM; EQUAL study investigators. Lombardi G, et al. Clin Kidney J. 2024 Aug 22;17(11):sfae254. doi: 10.1093/ckj/sfae254. eCollection 2024 Nov. Clin Kidney J. 2024. PMID: 39669396 Free PMC article.
Discovery of a Novel Mutant-Selective Epidermal Growth Factor Receptor Inhibitor Using an In Silico Enabled Drug Discovery Platform.
Igawa H, Konst ZA, Therrien E, Shelley M, Koldsø H, Bos PH, Negri A, Verras A, Guo J, Dahlgren MK, Levinson A, Parr BT, Kurhade SE, Latthe P, Shetty R, Santhanakrishnan S, Amberg-Johnson K, Futran AS, Atsriku C, Pelletier RD, Liu Z, Bell JA, Bhat S, Svensson M, Gerasyuto AI. Igawa H, et al. Among authors: svensson m. J Med Chem. 2024 Dec 26;67(24):21811-21840. doi: 10.1021/acs.jmedchem.4c01405. Epub 2024 Dec 12. J Med Chem. 2024. PMID: 39666597
The HLA-B -21 M/T dimorphism associates with disease severity in COVID-19.
Strunz B, Momayyezi P, Bilev E, Muvva JR, Chen P, Bister J, Schaffer M, Akber M, Cornillet M; Karolinska KI/K COVID-19 Study Group; Horowitz A, Malmberg KJ, Rooyackers O, Aleman S, Ljunggren HG, Björkström NK, Strålin K, Hammer Q. Strunz B, et al. Genes Immun. 2024 Nov 1. doi: 10.1038/s41435-024-00302-6. Online ahead of print. Genes Immun. 2024. PMID: 39487235
1,151 results