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The thienopyridine A-769662 and benzimidazole 991 inhibit human TASK-3 potassium channels in an AMPK-independent manner.
Biochem Pharmacol. 2024 Dec;230(Pt 1):116562. doi: 10.1016/j.bcp.2024.116562. Epub 2024 Oct 1.
Biochem Pharmacol. 2024.
PMID: 39362502
AMPK deficiency in smooth muscles causes persistent pulmonary hypertension of the new-born and premature death.
Moral-Sanz J, Lewis SA, MacMillan S, Meloni M, McClafferty H, Viollet B, Foretz M, Del-Pozo J, Mark Evans A.
Moral-Sanz J, et al. Among authors: mark evans a.
Nat Commun. 2022 Aug 26;13(1):5034. doi: 10.1038/s41467-022-32568-7.
Nat Commun. 2022.
PMID: 36028487
Free PMC article.
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Hypoxic pulmonary vasoconstriction--invited article.
Mark Evans A, Ward JP.
Mark Evans A, et al.
Adv Exp Med Biol. 2009;648:351-60. doi: 10.1007/978-90-481-2259-2_40.
Adv Exp Med Biol. 2009.
PMID: 19536499
Review.
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