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A senescence stress secretome is a hallmark of therapy-related myeloid neoplasm stromal tissue occurring soon after cytotoxic exposure.
Kutyna MM, Kok CH, Lim Y, Tran ENH, Campbell D, Paton S, Thompson-Peach C, Lim K, Cakouros D, Arthur A, Hughes T, Kumar S, Thomas D, Gronthos S, Hiwase DK. Kutyna MM, et al. Among authors: hughes t. Leukemia. 2022 Nov;36(11):2678-2689. doi: 10.1038/s41375-022-01686-y. Epub 2022 Aug 29. Leukemia. 2022. PMID: 36038666 Free PMC article.
Patients with chronic myeloid leukemia who maintain a complete molecular response after stopping imatinib treatment have evidence of persistent leukemia by DNA PCR.
Ross DM, Branford S, Seymour JF, Schwarer AP, Arthur C, Bartley PA, Slader C, Field C, Dang P, Filshie RJ, Mills AK, Grigg AP, Melo JV, Hughes TP. Ross DM, et al. Among authors: hughes tp. Leukemia. 2010 Oct;24(10):1719-24. doi: 10.1038/leu.2010.185. Epub 2010 Sep 2. Leukemia. 2010. PMID: 20811403
Do we have to kill the last CML cell?
Ross DM, Hughes TP, Melo JV. Ross DM, et al. Among authors: hughes tp. Leukemia. 2011 Feb;25(2):193-200. doi: 10.1038/leu.2010.197. Epub 2010 Sep 16. Leukemia. 2011. PMID: 20844563 Review.
3,066 results