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A senescence stress secretome is a hallmark of therapy-related myeloid neoplasm stromal tissue occurring soon after cytotoxic exposure.
Kutyna MM, Kok CH, Lim Y, Tran ENH, Campbell D, Paton S, Thompson-Peach C, Lim K, Cakouros D, Arthur A, Hughes T, Kumar S, Thomas D, Gronthos S, Hiwase DK. Kutyna MM, et al. Among authors: kok ch. Leukemia. 2022 Nov;36(11):2678-2689. doi: 10.1038/s41375-022-01686-y. Epub 2022 Aug 29. Leukemia. 2022. PMID: 36038666 Free PMC article.
TGF-α and IL-6 plasma levels selectively identify CML patients who fail to achieve an early molecular response or progress in the first year of therapy.
Nievergall E, Reynolds J, Kok CH, Watkins DB, Biondo M, Busfield SJ, Vairo G, Fuller K, Erber WN, Sadras T, Grose R, Yeung DT, Lopez AF, Hiwase DK, Hughes TP, White DL. Nievergall E, et al. Among authors: kok ch. Leukemia. 2016 Jun;30(6):1263-72. doi: 10.1038/leu.2016.34. Epub 2016 Feb 22. Leukemia. 2016. PMID: 26898188 Clinical Trial.
70 results