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A Broad Anti-influenza Hybrid Small Molecule That Potently Disrupts the Interaction of Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Subunits.
Massari S, Nannetti G, Desantis J, Muratore G, Sabatini S, Manfroni G, Mercorelli B, Cecchetti V, Palù G, Cruciani G, Loregian A, Goracci L, Tabarrini O. Massari S, et al. Among authors: desantis j. J Med Chem. 2015 May 14;58(9):3830-42. doi: 10.1021/acs.jmedchem.5b00012. Epub 2015 Apr 20. J Med Chem. 2015. PMID: 25856229 Free article.
Corrigendum to "Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity" [Eur. J. Med. Chem. 138 (2017) 128-139].
Desantis J, Nannetti G, Massari S, Barreca ML, Manfroni G, Cecchetti V, Palù G, Goracci L, Loregian A, Tabarrini O. Desantis J, et al. Eur J Med Chem. 2018 Aug 5;156:302-303. doi: 10.1016/j.ejmech.2018.07.009. Epub 2018 Jul 11. Eur J Med Chem. 2018. PMID: 30007243 No abstract available.
Indomethacin-based PROTACs as pan-coronavirus antiviral agents.
Desantis J, Mercorelli B, Celegato M, Croci F, Bazzacco A, Baroni M, Siragusa L, Cruciani G, Loregian A, Goracci L. Desantis J, et al. Eur J Med Chem. 2021 Dec 15;226:113814. doi: 10.1016/j.ejmech.2021.113814. Epub 2021 Sep 4. Eur J Med Chem. 2021. PMID: 34534839 Free PMC article.
Proteolysis targeting chimeras in antiviral research.
Desantis J, Goracci L. Desantis J, et al. Future Med Chem. 2022 Apr;14(7):459-462. doi: 10.4155/fmc-2022-0005. Epub 2022 Feb 8. Future Med Chem. 2022. PMID: 35134309 Free article. No abstract available.
78 results