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TBK1 and GABARAP family members suppress Coxsackievirus B infection by limiting viral production and promoting autophagic degradation of viral extracellular vesicles.
Sawaged S, Mota T, Piplani H, Thakur R, Lall D, McCabe E, Seo S, Sutterwala FS, Feuer R, Gottlieb RA, Sin J. Sawaged S, et al. Among authors: sutterwala fs. PLoS Pathog. 2022 Aug 31;18(8):e1010350. doi: 10.1371/journal.ppat.1010350. eCollection 2022 Aug. PLoS Pathog. 2022. PMID: 36044516 Free PMC article.
Recruitment of pro-IL-1α to mitochondrial cardiolipin, via shared LC3 binding domain, inhibits mitophagy and drives maximal NLRP3 activation.
Dagvadorj J, Mikulska-Ruminska K, Tumurkhuu G, Ratsimandresy RA, Carriere J, Andres AM, Marek-Iannucci S, Song Y, Chen S, Lane M, Dorfleutner A, Gottlieb RA, Stehlik C, Cassel S, Sutterwala FS, Bahar I, Crother TR, Arditi M. Dagvadorj J, et al. Among authors: sutterwala fs. Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e2015632118. doi: 10.1073/pnas.2015632118. Proc Natl Acad Sci U S A. 2021. PMID: 33361152 Free PMC article.
The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation.
Wang X, Shaw DK, Hammond HL, Sutterwala FS, Rayamajhi M, Shirey KA, Perkins DJ, Bonventre JV, Velayutham TS, Evans SM, Rodino KG, VieBrock L, Scanlon KM, Carbonetti NH, Carlyon JA, Miao EA, McBride JW, Kotsyfakis M, Pedra JH. Wang X, et al. Among authors: sutterwala fs. PLoS Pathog. 2016 Aug 2;12(8):e1005803. doi: 10.1371/journal.ppat.1005803. eCollection 2016 Aug. PLoS Pathog. 2016. PMID: 27482714 Free PMC article.
The Pseudomonas aeruginosa Type III Secretion System Exoenzyme Effector ExoU Induces Mitochondrial Damage in a Murine Bone Marrow-Derived Macrophage Infection Model.
Hardy KS, Tuckey AN, Housley NA, Andrews J, Patel M, Al-Mehdi AB, Barrington RA, Cassel SL, Sutterwala FS, Audia JP. Hardy KS, et al. Among authors: sutterwala fs. Infect Immun. 2022 Mar 17;90(3):e0047021. doi: 10.1128/IAI.00470-21. Epub 2022 Feb 7. Infect Immun. 2022. PMID: 35130452 Free PMC article.
The tiny conductor: immune regulation via commensal organisms.
Cassel SL, Sutterwala FS, Flavell RA. Cassel SL, et al. Among authors: sutterwala fs. Cell Host Microbe. 2008 Jun 12;3(6):340-1. doi: 10.1016/j.chom.2008.05.008. Cell Host Microbe. 2008. PMID: 18541208 Free article.
The Nalp3 inflammasome is essential for the development of silicosis.
Cassel SL, Eisenbarth SC, Iyer SS, Sadler JJ, Colegio OR, Tephly LA, Carter AB, Rothman PB, Flavell RA, Sutterwala FS. Cassel SL, et al. Among authors: sutterwala fs. Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):9035-40. doi: 10.1073/pnas.0803933105. Epub 2008 Jun 24. Proc Natl Acad Sci U S A. 2008. PMID: 18577586 Free PMC article.
117 results