Schleicher WE - Search Results

1

Reduced PU.1 Expression Collaborates with Tet2 Loss to Trigger Myeloid Leukemogenesis.

Schleicher WE, Pietras EM. Schleicher WE, et al. Blood Cancer Discov. 2022 Sep 6;3(5):378-381. doi: 10.1158/2643-3230.BCD-22-0100. Blood Cancer Discov. 2022. PMID: 36065607 Free PMC article.

2

CHIP: a clonal odyssey of the bone marrow niche.

Schleicher WE, Hoag B, De Dominici M, DeGregori J, Pietras EM. Schleicher WE, et al. J Clin Invest. 2024 Aug 1;134(15):e180068. doi: 10.1172/JCI180068. J Clin Invest. 2024. PMID: 39087468 Free PMC article. Review.

3

Modulation of Gap Junction Coupling Within the Islet of Langerhans During the Development of Type 1 Diabetes.

Farnsworth NL, Piscopio RA, Schleicher WE, Ramirez DG, Miranda JG, Benninger RKP. Farnsworth NL, et al. Among authors: schleicher we. Front Physiol. 2022 Jun 28;13:913611. doi: 10.3389/fphys.2022.913611. eCollection 2022. Front Physiol. 2022. PMID: 35837011 Free PMC article.

4

Functional architecture of pancreatic islets identifies a population of first responder cells that drive the first-phase calcium response.

Kravets V, Dwulet JM, Schleicher WE, Hodson DJ, Davis AM, Pyle L, Piscopio RA, Sticco-Ivins M, Benninger RKP. Kravets V, et al. Among authors: schleicher we. PLoS Biol. 2022 Sep 13;20(9):e3001761. doi: 10.1371/journal.pbio.3001761. eCollection 2022 Sep. PLoS Biol. 2022. PMID: 36099294 Free PMC article.

5

Dynamic changes in β-cell [Ca²⁺] regulate NFAT activation, gene transcription, and islet gap junction communication.

Miranda JG, Schleicher WE, Wells KL, Ramirez DG, Landgrave SP, Benninger RKP. Miranda JG, et al. Among authors: schleicher we. Mol Metab. 2022 Mar;57:101430. doi: 10.1016/j.molmet.2021.101430. Epub 2021 Dec 31. Mol Metab. 2022. PMID: 34979329 Free PMC article.

6

How Heterogeneity in Glucokinase and Gap-Junction Coupling Determines the Islet [Ca²⁺] Response.

Dwulet JM, Ludin NWF, Piscopio RA, Schleicher WE, Moua O, Westacott MJ, Benninger RKP. Dwulet JM, et al. Among authors: schleicher we. Biophys J. 2019 Dec 3;117(11):2188-2203. doi: 10.1016/j.bpj.2019.10.037. Epub 2019 Nov 5. Biophys J. 2019. PMID: 31753287 Free PMC article.

7

Caloric restriction recovers impaired β-cell-β-cell gap junction coupling, calcium oscillation coordination, and insulin secretion in prediabetic mice.

Corezola do Amaral ME, Kravets V, Dwulet JM, Farnsworth NL, Piscopio R, Schleicher WE, Miranda JG, Benninger RKP. Corezola do Amaral ME, et al. Among authors: schleicher we. Am J Physiol Endocrinol Metab. 2020 Oct 1;319(4):E709-E720. doi: 10.1152/ajpendo.00132.2020. Epub 2020 Aug 24. Am J Physiol Endocrinol Metab. 2020. PMID: 32830549 Free PMC article.

8

Restoring connexin-36 function in diabetogenic environments precludes mouse and human islet dysfunction.

St Clair JR, Westacott MJ, Miranda J, Farnsworth NL, Kravets V, Schleicher WE, Dwulet JM, Levitt CH, Heintz A, Ludin NWF, Benninger RKP. St Clair JR, et al. Among authors: schleicher we. J Physiol. 2023 Sep;601(18):4053-4072. doi: 10.1113/JP282114. Epub 2023 Aug 14. J Physiol. 2023. PMID: 37578890 Free PMC article.

9

Exendin-4 overcomes cytokine-induced decreases in gap junction coupling via protein kinase A and Epac2 in mouse and human islets.

Farnsworth NL, Walter R, Piscopio RA, Schleicher WE, Benninger RKP. Farnsworth NL, et al. Among authors: schleicher we. J Physiol. 2019 Jan;597(2):431-447. doi: 10.1113/JP276106. Epub 2018 Nov 29. J Physiol. 2019. PMID: 30412665 Free PMC article.

10

Optogenetic stimulation of cholinergic fibers for the modulation of insulin and glycemia.

Fontaine AK, Ramirez DG, Littich SF, Piscopio RA, Kravets V, Schleicher WE, Mizoguchi N, Caldwell JH, Weir RFF, Benninger RKP. Fontaine AK, et al. Among authors: schleicher we. Sci Rep. 2021 Feb 11;11(1):3670. doi: 10.1038/s41598-021-83361-3. Sci Rep. 2021. PMID: 33574598 Free PMC article.

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