Moraes CB - Search Results

1

Antiviral activity of Cenostigma pluviosum var. peltophoroides extract and fractions against SARS-CoV-2.

Pattaro-Júnior JR, Araújo IG, Moraes CB, Barbosa CG, Philippsen GS, Freitas-Junior LH, Guidi AC, de Mello JCP, Peralta RM, Fernandez MA, Teixeira RR, Seixas FAV. Pattaro-Júnior JR, et al. Among authors: moraes cb. J Biomol Struct Dyn. 2023 Sep-Oct;41(15):7297-7308. doi: 10.1080/07391102.2022.2120078. Epub 2022 Sep 7. J Biomol Struct Dyn. 2023. PMID: 36069130

2

An essential nuclear protein in trypanosomes is a component of mRNA transcription/export pathway.

Serpeloni M, Moraes CB, Muniz JR, Motta MC, Ramos AS, Kessler RL, Inoue AH, daRocha WD, Yamada-Ogatta SF, Fragoso SP, Goldenberg S, Freitas-Junior LH, Avila AR. Serpeloni M, et al. Among authors: moraes cb. PLoS One. 2011;6(6):e20730. doi: 10.1371/journal.pone.0020730. Epub 2011 Jun 8. PLoS One. 2011. PMID: 21687672 Free PMC article.

3

Amazonian plant natural products: perspectives for discovery of new antimalarial drug leads.

Pohlit AM, Lima RB, Frausin G, Silva LF, Lopes SC, Moraes CB, Cravo P, Lacerda MV, Siqueira AM, Freitas-Junior LH, Costa FT. Pohlit AM, et al. Among authors: moraes cb. Molecules. 2013 Aug 2;18(8):9219-40. doi: 10.3390/molecules18089219. Molecules. 2013. PMID: 23917112 Free PMC article. Review.

4

Nitroheterocyclic compounds are more efficacious than CYP51 inhibitors against Trypanosoma cruzi: implications for Chagas disease drug discovery and development.

Moraes CB, Giardini MA, Kim H, Franco CH, Araujo-Junior AM, Schenkman S, Chatelain E, Freitas-Junior LH. Moraes CB, et al. Sci Rep. 2014 Apr 16;4:4703. doi: 10.1038/srep04703. Sci Rep. 2014. PMID: 24736467 Free PMC article.

5

Drug discovery for human African trypanosomiasis: identification of novel scaffolds by the newly developed HTS SYBR Green assay for Trypanosoma brucei.

Faria J, Moraes CB, Song R, Pascoalino BS, Lee N, Siqueira-Neto JL, Cruz DJ, Parkinson T, Ioset JR, Cordeiro-da-Silva A, Freitas-Junior LH. Faria J, et al. Among authors: moraes cb. J Biomol Screen. 2015 Jan;20(1):70-81. doi: 10.1177/1087057114556236. Epub 2014 Oct 23. J Biomol Screen. 2015. PMID: 25342146

6

Design, synthesis and antitrypanosomal activity of some nitrofurazone 1,2,4-triazolic bioisosteric analogues.

Silva FT, Franco CH, Favaro DC, Freitas-Junior LH, Moraes CB, Ferreira EI. Silva FT, et al. Among authors: moraes cb. Eur J Med Chem. 2016 Oct 4;121:553-560. doi: 10.1016/j.ejmech.2016.04.065. Epub 2016 Jun 1. Eur J Med Chem. 2016. PMID: 27318979

7

Synthesis and trypanocidal activity of a library of 4-substituted 2-(1H-pyrrolo[3,2-c]pyridin-2-yl)propan-2-ols.

Balfour MN, Franco CH, Moraes CB, Freitas-Junior LH, Stefani HA. Balfour MN, et al. Among authors: moraes cb. Eur J Med Chem. 2017 Mar 10;128:202-212. doi: 10.1016/j.ejmech.2017.01.040. Epub 2017 Feb 3. Eur J Med Chem. 2017. PMID: 28189084

8

Computer-aided discovery of two novel chalcone-like compounds active and selective against Leishmania infantum.

Gomes MN, Alcântara LM, Neves BJ, Melo-Filho CC, Freitas-Junior LH, Moraes CB, Ma R, Franzblau SG, Muratov E, Andrade CH. Gomes MN, et al. Among authors: moraes cb. Bioorg Med Chem Lett. 2017 Jun 1;27(11):2459-2464. doi: 10.1016/j.bmcl.2017.04.010. Epub 2017 Apr 4. Bioorg Med Chem Lett. 2017. PMID: 28434763 Free PMC article.

9

Aryl thiosemicarbazones for the treatment of trypanosomatidic infections.

Linciano P, Moraes CB, Alcantara LM, Franco CH, Pascoalino B, Freitas-Junior LH, Macedo S, Santarem N, Cordeiro-da-Silva A, Gul S, Witt G, Kuzikov M, Ellinger B, Ferrari S, Luciani R, Quotadamo A, Costantino L, Costi MP. Linciano P, et al. Among authors: moraes cb. Eur J Med Chem. 2018 Feb 25;146:423-434. doi: 10.1016/j.ejmech.2018.01.043. Epub 2018 Jan 31. Eur J Med Chem. 2018. PMID: 29407968

10

Discovery of new potent hits against intracellular Trypanosoma cruzi by QSAR-based virtual screening.

Melo-Filho CC, Braga RC, Muratov EN, Franco CH, Moraes CB, Freitas-Junior LH, Andrade CH. Melo-Filho CC, et al. Among authors: moraes cb. Eur J Med Chem. 2019 Feb 1;163:649-659. doi: 10.1016/j.ejmech.2018.11.062. Epub 2018 Nov 29. Eur J Med Chem. 2019. PMID: 30562700

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