Lemberg MK - Search Results

1

Lysosomal enzyme trafficking factor LYSET enables nutritional usage of extracellular proteins.

Pechincha C, Groessl S, Kalis R, de Almeida M, Zanotti A, Wittmann M, Schneider M, de Campos RP, Rieser S, Brandstetter M, Schleiffer A, Müller-Decker K, Helm D, Jabs S, Haselbach D, Lemberg MK, Zuber J, Palm W. Pechincha C, et al. Among authors: lemberg mk. Science. 2022 Oct 7;378(6615):eabn5637. doi: 10.1126/science.abn5637. Epub 2022 Oct 7. Science. 2022. PMID: 36074822

2

The human signal peptidase complex acts as a quality control enzyme for membrane proteins.

Zanotti A, Coelho JPL, Kaylani D, Singh G, Tauber M, Hitzenberger M, Avci D, Zacharias M, Russell RB, Lemberg MK, Feige MJ. Zanotti A, et al. Among authors: lemberg mk. Science. 2022 Dec 2;378(6623):996-1000. doi: 10.1126/science.abo5672. Epub 2022 Dec 1. Science. 2022. PMID: 36454823

3

Rhomboid intramembrane protease RHBDL4 triggers ER-export and non-canonical secretion of membrane-anchored TGFα.

Wunderle L, Knopf JD, Kühnle N, Morlé A, Hehn B, Adrain C, Strisovsky K, Freeman M, Lemberg MK. Wunderle L, et al. Among authors: lemberg mk. Sci Rep. 2016 Jun 6;6:27342. doi: 10.1038/srep27342. Sci Rep. 2016. PMID: 27264103 Free PMC article.

4

The intramembrane protease SPP impacts morphology of the endoplasmic reticulum by triggering degradation of morphogenic proteins.

Avci D, Malchus NS, Heidasch R, Lorenz H, Richter K, Neßling M, Lemberg MK. Avci D, et al. Among authors: lemberg mk. J Biol Chem. 2019 Feb 22;294(8):2786-2800. doi: 10.1074/jbc.RA118.005642. Epub 2018 Dec 21. J Biol Chem. 2019. PMID: 30578301 Free PMC article.

5

Rhomboid protease RHBDL4 promotes retrotranslocation of aggregation-prone proteins for degradation.

Bock J, Kühnle N, Knopf JD, Landscheidt N, Lee JG, Ye Y, Lemberg MK. Bock J, et al. Among authors: lemberg mk. Cell Rep. 2022 Aug 9;40(6):111175. doi: 10.1016/j.celrep.2022.111175. Cell Rep. 2022. PMID: 35947953 Free PMC article.

6

Intramembrane proteolysis at a glance: from signalling to protein degradation.

Kühnle N, Dederer V, Lemberg MK. Kühnle N, et al. Among authors: lemberg mk. J Cell Sci. 2019 Aug 15;132(16):jcs217745. doi: 10.1242/jcs.217745. J Cell Sci. 2019. PMID: 31416853 Review.

7

Signal Peptide Peptidase-Type Proteases: Versatile Regulators with Functions Ranging from Limited Proteolysis to Protein Degradation.

Yücel SS, Lemberg MK. Yücel SS, et al. Among authors: lemberg mk. J Mol Biol. 2020 Aug 21;432(18):5063-5078. doi: 10.1016/j.jmb.2020.05.014. Epub 2020 May 26. J Mol Biol. 2020. PMID: 32464132 Review.

8

Transmembrane dislocases: a second chance for protein targeting.

Dederer V, Lemberg MK. Dederer V, et al. Among authors: lemberg mk. Trends Cell Biol. 2021 Nov;31(11):898-911. doi: 10.1016/j.tcb.2021.05.007. Epub 2021 Jun 16. Trends Cell Biol. 2021. PMID: 34147299 Review.

9

Mechanism of intramembrane proteolysis investigated with purified rhomboid proteases.

Lemberg MK, Menendez J, Misik A, Garcia M, Koth CM, Freeman M. Lemberg MK, et al. EMBO J. 2005 Feb 9;24(3):464-72. doi: 10.1038/sj.emboj.7600537. Epub 2004 Dec 23. EMBO J. 2005. PMID: 15616571 Free PMC article.

10

Functional and evolutionary implications of enhanced genomic analysis of rhomboid intramembrane proteases.

Lemberg MK, Freeman M. Lemberg MK, et al. Genome Res. 2007 Nov;17(11):1634-46. doi: 10.1101/gr.6425307. Epub 2007 Oct 15. Genome Res. 2007. PMID: 17938163 Free PMC article.

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