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Page 1
Lysosomal enzyme trafficking factor LYSET enables nutritional usage of extracellular proteins.
Pechincha C, Groessl S, Kalis R, de Almeida M, Zanotti A, Wittmann M, Schneider M, de Campos RP, Rieser S, Brandstetter M, Schleiffer A, Müller-Decker K, Helm D, Jabs S, Haselbach D, Lemberg MK, Zuber J, Palm W. Pechincha C, et al. Among authors: schleiffer a. Science. 2022 Oct 7;378(6615):eabn5637. doi: 10.1126/science.abn5637. Epub 2022 Oct 7. Science. 2022. PMID: 36074822
Multilayered VBC score predicts sgRNAs that efficiently generate loss-of-function alleles.
Michlits G, Jude J, Hinterndorfer M, de Almeida M, Vainorius G, Hubmann M, Neumann T, Schleiffer A, Burkard TR, Fellner M, Gijsbertsen M, Traunbauer A, Zuber J, Elling U. Michlits G, et al. Among authors: schleiffer a. Nat Methods. 2020 Jul;17(7):708-716. doi: 10.1038/s41592-020-0850-8. Epub 2020 Jun 8. Nat Methods. 2020. PMID: 32514112
AKIRIN2 controls the nuclear import of proteasomes in vertebrates.
de Almeida M, Hinterndorfer M, Brunner H, Grishkovskaya I, Singh K, Schleiffer A, Jude J, Deswal S, Kalis R, Vunjak M, Lendl T, Imre R, Roitinger E, Neumann T, Kandolf S, Schutzbier M, Mechtler K, Versteeg GA, Haselbach D, Zuber J. de Almeida M, et al. Among authors: schleiffer a. Nature. 2021 Nov;599(7885):491-496. doi: 10.1038/s41586-021-04035-8. Epub 2021 Oct 28. Nature. 2021. PMID: 34711951
Cryo-EM structure of the plant 26S proteasome.
Kandolf S, Grishkovskaya I, Belačić K, Bolhuis DL, Amann S, Foster B, Imre R, Mechtler K, Schleiffer A, Tagare HD, Zhong ED, Meinhart A, Brown NG, Haselbach D. Kandolf S, et al. Among authors: schleiffer a. Plant Commun. 2022 May 9;3(3):100310. doi: 10.1016/j.xplc.2022.100310. Epub 2022 Mar 11. Plant Commun. 2022. PMID: 35576154 Free PMC article.
Cryo-EM structure of the chain-elongating E3 ubiquitin ligase UBR5.
Hodáková Z, Grishkovskaya I, Brunner HL, Bolhuis DL, Belačić K, Schleiffer A, Kotisch H, Brown NG, Haselbach D. Hodáková Z, et al. Among authors: schleiffer a. EMBO J. 2023 Aug 15;42(16):e113348. doi: 10.15252/embj.2022113348. Epub 2023 Jul 6. EMBO J. 2023. PMID: 37409633 Free PMC article.
Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Hutchins JR, Toyoda Y, Hegemann B, Poser I, Hériché JK, Sykora MM, Augsburg M, Hudecz O, Buschhorn BA, Bulkescher J, Conrad C, Comartin D, Schleiffer A, Sarov M, Pozniakovsky A, Slabicki MM, Schloissnig S, Steinmacher I, Leuschner M, Ssykor A, Lawo S, Pelletier L, Stark H, Nasmyth K, Ellenberg J, Durbin R, Buchholz F, Mechtler K, Hyman AA, Peters JM. Hutchins JR, et al. Among authors: schleiffer a. Science. 2010 Apr 30;328(5978):593-9. doi: 10.1126/science.1181348. Epub 2010 Apr 1. Science. 2010. PMID: 20360068 Free PMC article.
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