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Page 1
Understanding the dynamic relation between wastewater SARS-CoV-2 signal and clinical metrics throughout the pandemic.
Hegazy N, Cowan A, D'Aoust PM, Mercier É, Towhid ST, Jia JJ, Wan S, Zhang Z, Kabir MP, Fang W, Graber TE, MacKenzie AE, Guilherme S, Delatolla R. Hegazy N, et al. Among authors: jia jj. Sci Total Environ. 2022 Dec 20;853:158458. doi: 10.1016/j.scitotenv.2022.158458. Epub 2022 Sep 6. Sci Total Environ. 2022. PMID: 36075428 Free PMC article.
La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1).
Fonseca BD, Zakaria C, Jia JJ, Graber TE, Svitkin Y, Tahmasebi S, Healy D, Hoang HD, Jensen JM, Diao IT, Lussier A, Dajadian C, Padmanabhan N, Wang W, Matta-Camacho E, Hearnden J, Smith EM, Tsukumo Y, Yanagiya A, Morita M, Petroulakis E, González JL, Hernández G, Alain T, Damgaard CK. Fonseca BD, et al. Among authors: jia jj. J Biol Chem. 2015 Jun 26;290(26):15996-6020. doi: 10.1074/jbc.M114.621730. Epub 2015 May 4. J Biol Chem. 2015. PMID: 25940091 Free PMC article.
Quantitative analysis of SARS-CoV-2 RNA from wastewater solids in communities with low COVID-19 incidence and prevalence.
D'Aoust PM, Mercier E, Montpetit D, Jia JJ, Alexandrov I, Neault N, Baig AT, Mayne J, Zhang X, Alain T, Langlois MA, Servos MR, MacKenzie M, Figeys D, MacKenzie AE, Graber TE, Delatolla R. D'Aoust PM, et al. Among authors: jia jj. Water Res. 2021 Jan 1;188:116560. doi: 10.1016/j.watres.2020.116560. Epub 2020 Oct 23. Water Res. 2021. PMID: 33137526 Free PMC article.
mTORC1 promotes TOP mRNA translation through site-specific phosphorylation of LARP1.
Jia JJ, Lahr RM, Solgaard MT, Moraes BJ, Pointet R, Yang AD, Celucci G, Graber TE, Hoang HD, Niklaus MR, Pena IA, Hollensen AK, Smith EM, Chaker-Margot M, Anton L, Dajadian C, Livingstone M, Hearnden J, Wang XD, Yu Y, Maier T, Damgaard CK, Berman AJ, Alain T, Fonseca BD. Jia JJ, et al. Nucleic Acids Res. 2021 Apr 6;49(6):3461-3489. doi: 10.1093/nar/gkaa1239. Nucleic Acids Res. 2021. PMID: 33398329 Free PMC article.
Wastewater to clinical case (WC) ratio of COVID-19 identifies insufficient clinical testing, onset of new variants of concern and population immunity in urban communities.
D'Aoust PM, Tian X, Towhid ST, Xiao A, Mercier E, Hegazy N, Jia JJ, Wan S, Kabir MP, Fang W, Fuzzen M, Hasing M, Yang MI, Sun J, Plaza-Diaz J, Zhang Z, Cowan A, Eid W, Stephenson S, Servos MR, Wade MJ, MacKenzie AE, Peng H, Edwards EA, Pang XL, Alm EJ, Graber TE, Delatolla R. D'Aoust PM, et al. Among authors: jia jj. Sci Total Environ. 2022 Dec 20;853:158547. doi: 10.1016/j.scitotenv.2022.158547. Epub 2022 Sep 5. Sci Total Environ. 2022. PMID: 36067855 Free PMC article.
Rapidly developed, optimized, and applied wastewater surveillance system for real-time monitoring of low-incidence, high-impact MPOX outbreak.
Wong CH, Zhang Z, Eid W, Plaza-Diaz J, Kabir P, Wan S, Jia JJ, Mercier E, Thakali O, Pisharody L, Hegazy N, Stephenson SE, Fang W, Nguyen TB, Ramsay NT, McKay RM, Corchis-Scott R, MacKenzie AE, Graber TE, D' Aoust PM, Delatolla R. Wong CH, et al. Among authors: jia jj. J Water Health. 2023 Sep;21(9):1264-1276. doi: 10.2166/wh.2023.145. J Water Health. 2023. PMID: 37756194
Effective method to mitigate impact of rain or snowmelt sewer flushing events on wastewater-based surveillance measurements.
Mercier E, D'Aoust PM, Renouf E, Tomalty E, Addo FG, Nguyen TB, Wong CH, Ramsay NT, Tian X, Hegazy N, Kabir MP, Jia JJ, Wan S, Pisharody L, Szulc P, MacKenzie AE, Delatolla R. Mercier E, et al. Among authors: jia jj. Sci Total Environ. 2024 Dec 15;956:177351. doi: 10.1016/j.scitotenv.2024.177351. Epub 2024 Nov 5. Sci Total Environ. 2024. PMID: 39489448 Free article.
Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis.
Zakaria C, Sean P, Hoang HD, Leroux LP, Watson M, Workenhe ST, Hearnden J, Pearl D, Truong VT, Robichaud N, Yanagiya A, Tahmasebi S, Jafarnejad SM, Jia JJ, Pelin A, Diallo JS, Le Boeuf F, Bell JC, Mossman KL, Graber TE, Jaramillo M, Sonenberg N, Alain T. Zakaria C, et al. Among authors: jia jj. PLoS Pathog. 2018 Aug 23;14(8):e1007264. doi: 10.1371/journal.ppat.1007264. eCollection 2018 Aug. PLoS Pathog. 2018. PMID: 30138450 Free PMC article.
144 results