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SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein.
Walter M, Chen IP, Vallejo-Gracia A, Kim IJ, Bielska O, Lam VL, Hayashi JM, Cruz A, Shah S, Soveg FW, Gross JD, Krogan NJ, Jerome KR, Schilling B, Ott M, Verdin E. Walter M, et al. Among authors: chen ip. PLoS Pathog. 2022 Sep 12;18(9):e1010811. doi: 10.1371/journal.ppat.1010811. eCollection 2022 Sep. PLoS Pathog. 2022. PMID: 36095012 Free PMC article.
FOXO1 promotes HIV latency by suppressing ER stress in T cells.
Vallejo-Gracia A, Chen IP, Perrone R, Besnard E, Boehm D, Battivelli E, Tezil T, Krey K, Raymond KA, Hull PA, Walter M, Habrylo I, Cruz A, Deeks S, Pillai S, Verdin E, Ott M. Vallejo-Gracia A, et al. Among authors: chen ip. Nat Microbiol. 2020 Sep;5(9):1144-1157. doi: 10.1038/s41564-020-0742-9. Epub 2020 Jun 15. Nat Microbiol. 2020. PMID: 32541947 Free PMC article.
Turning up the heat on HIV-1.
Chen IP, Ott M. Chen IP, et al. Proc Natl Acad Sci U S A. 2020 Jul 14;117(28):16109-16111. doi: 10.1073/pnas.2010212117. Epub 2020 Jun 30. Proc Natl Acad Sci U S A. 2020. PMID: 32606243 Free PMC article. No abstract available.
Rapid assessment of SARS-CoV-2-evolved variants using virus-like particles.
Syed AM, Taha TY, Tabata T, Chen IP, Ciling A, Khalid MM, Sreekumar B, Chen PY, Hayashi JM, Soczek KM, Ott M, Doudna JA. Syed AM, et al. Among authors: chen py, chen ip. Science. 2021 Dec 24;374(6575):1626-1632. doi: 10.1126/science.abl6184. Epub 2021 Nov 4. Science. 2021. PMID: 34735219 Free PMC article.
Viral E Protein Neutralizes BET Protein-Mediated Post-Entry Antagonism of SARS-CoV-2.
Chen IP, Longbotham JE, McMahon S, Suryawanshi RK, Carlson-Stevermer J, Gupta M, Zhang MY, Soveg FW, Hayashi JM, Taha TY, Lam VL, Li Y, Yu Z, Titus EW, Diallo A, Oki J, Holden K; QCRG Structural Biology Consortium; Krogan N, Galonić Fujimori D, Ott M. Chen IP, et al. bioRxiv [Preprint]. 2021 Nov 15:2021.11.14.468537. doi: 10.1101/2021.11.14.468537. bioRxiv. 2021. Update in: Cell Rep. 2022 Jul 19;40(3):111088. doi: 10.1016/j.celrep.2022.111088 PMID: 34816261 Free PMC article. Updated. Preprint.
Omicron mutations enhance infectivity and reduce antibody neutralization of SARS-CoV-2 virus-like particles.
Syed AM, Ciling A, Khalid MM, Sreekumar B, Chen PY, Kumar GR, Silva I, Milbes B, Kojima N, Hess V, Shacreaw M, Lopez L, Brobeck M, Turner F, Spraggon L, Taha TY, Tabata T, Chen IP, Ott M, Doudna JA. Syed AM, et al. Among authors: chen py, chen ip. medRxiv [Preprint]. 2022 Jan 2:2021.12.20.21268048. doi: 10.1101/2021.12.20.21268048. medRxiv. 2022. Update in: Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2200592119. doi: 10.1073/pnas.2200592119 PMID: 34981067 Free PMC article. Updated. Preprint.
SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein.
Walter M, Chen IP, Vallejo-Gracia A, Kim IJ, Bielska O, Lam VL, Hayashi JM, Cruz A, Shah S, Gross JD, Krogan NJ, Schilling B, Ott M, Verdin E. Walter M, et al. Among authors: chen ip. bioRxiv [Preprint]. 2022 Jan 5:2022.01.04.474979. doi: 10.1101/2022.01.04.474979. bioRxiv. 2022. Update in: PLoS Pathog. 2022 Sep 12;18(9):e1010811. doi: 10.1371/journal.ppat.1010811 PMID: 35018374 Free PMC article. Updated. Preprint.
Limited Cross-Variant Immunity after Infection with the SARS-CoV-2 Omicron Variant Without Vaccination.
Suryawanshi RK, Chen IP, Ma T, Syed AM, Brazer N, Saldhi P, Simoneau CR, Ciling A, Khalid MM, Sreekumar B, Chen PY, Kumar GR, Montano M, Garcia-Knight MA, Sotomayor-Gonzalez A, Servellita V, Gliwa A, Nguyen J, Silva I, Milbes B, Kojima N, Hess V, Shacreaw M, Lopez L, Brobeck M, Turner F, Soveg FW, George AF, Fang X, Maishan M, Matthay M, Greene WC, Andino R, Spraggon L, Roan NR, Chiu CY, Doudna J, Ott M. Suryawanshi RK, et al. Among authors: chen py, chen ip. medRxiv [Preprint]. 2022 Feb 9:2022.01.13.22269243. doi: 10.1101/2022.01.13.22269243. medRxiv. 2022. Update in: Nature. 2022 Jul;607(7918):351-355. doi: 10.1038/s41586-022-04865-0 PMID: 35075459 Free PMC article. Updated. Preprint.
Limited cross-variant immunity from SARS-CoV-2 Omicron without vaccination.
Suryawanshi RK, Chen IP, Ma T, Syed AM, Brazer N, Saldhi P, Simoneau CR, Ciling A, Khalid MM, Sreekumar B, Chen PY, Kumar GR, Montano M, Gascon R, Tsou CL, Garcia-Knight MA, Sotomayor-Gonzalez A, Servellita V, Gliwa A, Nguyen J, Silva I, Milbes B, Kojima N, Hess V, Shacreaw M, Lopez L, Brobeck M, Turner F, Soveg FW, George AF, Fang X, Maishan M, Matthay M, Morris MK, Wadford D, Hanson C, Greene WC, Andino R, Spraggon L, Roan NR, Chiu CY, Doudna JA, Ott M. Suryawanshi RK, et al. Among authors: chen py, chen ip. Nature. 2022 Jul;607(7918):351-355. doi: 10.1038/s41586-022-04865-0. Epub 2022 May 18. Nature. 2022. PMID: 35584773 Free PMC article.
Viral E protein neutralizes BET protein-mediated post-entry antagonism of SARS-CoV-2.
Chen IP, Longbotham JE, McMahon S, Suryawanshi RK, Khalid MM, Taha TY, Tabata T, Hayashi JM, Soveg FW, Carlson-Stevermer J, Gupta M, Zhang MY, Lam VL, Li Y, Yu Z, Titus EW, Diallo A, Oki J, Holden K, Krogan N, Fujimori DG, Ott M. Chen IP, et al. Cell Rep. 2022 Jul 19;40(3):111088. doi: 10.1016/j.celrep.2022.111088. Epub 2022 Jun 27. Cell Rep. 2022. PMID: 35839775 Free PMC article.
113 results