Ott M - Search Results

1

SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein.

Walter M, Chen IP, Vallejo-Gracia A, Kim IJ, Bielska O, Lam VL, Hayashi JM, Cruz A, Shah S, Soveg FW, Gross JD, Krogan NJ, Jerome KR, Schilling B, Ott M, Verdin E. Walter M, et al. Among authors: ott m. PLoS Pathog. 2022 Sep 12;18(9):e1010811. doi: 10.1371/journal.ppat.1010811. eCollection 2022 Sep. PLoS Pathog. 2022. PMID: 36095012 Free PMC article.

2

The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase.

Schwer B, North BJ, Frye RA, Ott M, Verdin E. Schwer B, et al. Among authors: ott m. J Cell Biol. 2002 Aug 19;158(4):647-57. doi: 10.1083/jcb.200205057. Epub 2002 Aug 19. J Cell Biol. 2002. PMID: 12186850 Free PMC article.

3

Tat acetylation: a regulatory switch between early and late phases in HIV transcription elongation.

Ott M, Dorr A, Hetzer-Egger C, Kaehlcke K, Schnolzer M, Henklein P, Cole P, Zhou MM, Verdin E. Ott M, et al. Novartis Found Symp. 2004;259:182-93; discussion 193-6, 223-5. Novartis Found Symp. 2004. PMID: 15171254 Review.

4

SIRT1 regulates HIV transcription via Tat deacetylation.

Pagans S, Pedal A, North BJ, Kaehlcke K, Marshall BL, Dorr A, Hetzer-Egger C, Henklein P, Frye R, McBurney MW, Hruby H, Jung M, Verdin E, Ott M. Pagans S, et al. Among authors: ott m. PLoS Biol. 2005 Feb;3(2):e41. doi: 10.1371/journal.pbio.0030041. Epub 2005 Feb 8. PLoS Biol. 2005. PMID: 15719057 Free PMC article.

5

The SWI/SNF chromatin-remodeling complex is a cofactor for Tat transactivation of the HIV promoter.

Mahmoudi T, Parra M, Vries RG, Kauder SE, Verrijzer CP, Ott M, Verdin E. Mahmoudi T, et al. Among authors: ott m. J Biol Chem. 2006 Jul 21;281(29):19960-8. doi: 10.1074/jbc.M603336200. Epub 2006 May 10. J Biol Chem. 2006. PMID: 16687403 Free article.

6

The Cellular lysine methyltransferase Set7/9-KMT7 binds HIV-1 TAR RNA, monomethylates the viral transactivator Tat, and enhances HIV transcription.

Pagans S, Kauder SE, Kaehlcke K, Sakane N, Schroeder S, Dormeyer W, Trievel RC, Verdin E, Schnolzer M, Ott M. Pagans S, et al. Among authors: ott m. Cell Host Microbe. 2010 Mar 18;7(3):234-44. doi: 10.1016/j.chom.2010.02.005. Cell Host Microbe. 2010. PMID: 20227666 Free PMC article.

7

HAT trick: p300, small molecule, inhibitor.

Ott M, Verdin E. Ott M, et al. Chem Biol. 2010 May 28;17(5):417-8. doi: 10.1016/j.chembiol.2010.05.002. Chem Biol. 2010. PMID: 20534339

8

Two-pronged binding with bromodomain-containing protein 4 liberates positive transcription elongation factor b from inactive ribonucleoprotein complexes.

Schröder S, Cho S, Zeng L, Zhang Q, Kaehlcke K, Mak L, Lau J, Bisgrove D, Schnölzer M, Verdin E, Zhou MM, Ott M. Schröder S, et al. Among authors: ott m. J Biol Chem. 2012 Jan 6;287(2):1090-9. doi: 10.1074/jbc.M111.282855. Epub 2011 Nov 14. J Biol Chem. 2012. PMID: 22084242 Free PMC article.

9

Three novel acetylation sites in the Foxp3 transcription factor regulate the suppressive activity of regulatory T cells.

Kwon HS, Lim HW, Wu J, Schnölzer M, Verdin E, Ott M. Kwon HS, et al. Among authors: ott m. J Immunol. 2012 Mar 15;188(6):2712-21. doi: 10.4049/jimmunol.1100903. Epub 2012 Feb 6. J Immunol. 2012. PMID: 22312127 Free PMC article.

10

BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism.

Boehm D, Calvanese V, Dar RD, Xing S, Schroeder S, Martins L, Aull K, Li PC, Planelles V, Bradner JE, Zhou MM, Siliciano RF, Weinberger L, Verdin E, Ott M. Boehm D, et al. Among authors: ott m. Cell Cycle. 2013 Feb 1;12(3):452-62. doi: 10.4161/cc.23309. Epub 2012 Feb 1. Cell Cycle. 2013. PMID: 23255218 Free PMC article.

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