Fak J - Search Results

1

Increased p53 expression induced by APR-246 reprograms tumor-associated macrophages to augment immune checkpoint blockade.

Ghosh A, Michels J, Mezzadra R, Venkatesh D, Dong L, Gomez R, Samaan F, Ho YJ, Campesato LF, Mangarin L, Fak J, Suek N, Holland A, Liu C, Abu-Akeel M, Bykov Y, Zhong H, Fitzgerald K, Budhu S, Chow A, Zappasodi R, Panageas KS, de Henau O, Ruscetti M, Lowe SW, Merghoub T, Wolchok JD. Ghosh A, et al. Among authors: fak j. J Clin Invest. 2022 Sep 15;132(18):e148141. doi: 10.1172/JCI148141. J Clin Invest. 2022. PMID: 36106631 Free PMC article.

2

Patients with lung cancer and paraneoplastic Hu syndrome harbor HuD-specific type 2 CD8+ T cells.

Roberts WK, Deluca IJ, Thomas A, Fak J, Williams T, Buckley N, Dousmanis AG, Posner JB, Darnell RB. Roberts WK, et al. Among authors: fak j. J Clin Invest. 2009 Jul;119(7):2042-51. doi: 10.1172/JCI36131. Epub 2009 Jun 8. J Clin Invest. 2009. PMID: 19509467 Free PMC article.

3

ZFP36 RNA-binding proteins restrain T cell activation and anti-viral immunity.

Moore MJ, Blachere NE, Fak JJ, Park CY, Sawicka K, Parveen S, Zucker-Scharff I, Moltedo B, Rudensky AY, Darnell RB. Moore MJ, et al. Among authors: fak jj. Elife. 2018 May 31;7:e33057. doi: 10.7554/eLife.33057. Elife. 2018. PMID: 29848443 Free PMC article.

4

T cells targeting a neuronal paraneoplastic antigen mediate tumor rejection and trigger CNS autoimmunity with humoral activation.

Blachère NE, Orange DE, Santomasso BD, Doerner J, Foo PK, Herre M, Fak J, Monette S, Gantman EC, Frank MO, Darnell RB. Blachère NE, et al. Among authors: fak j. Eur J Immunol. 2014 Nov;44(11):3240-51. doi: 10.1002/eji.201444624. Eur J Immunol. 2014. PMID: 25103845 Free PMC article.

5

Neuronal activity rapidly reprograms dendritic translation via eIF4G2:uORF binding.

Hacisuleyman E, Hale CR, Noble N, Luo JD, Fak JJ, Saito M, Chen J, Weissman JS, Darnell RB. Hacisuleyman E, et al. Among authors: fak jj. Nat Neurosci. 2024 May;27(5):822-835. doi: 10.1038/s41593-024-01615-5. Epub 2024 Apr 8. Nat Neurosci. 2024. PMID: 38589584 Free PMC article.

6

HITS-CLIP yields genome-wide insights into brain alternative RNA processing.

Licatalosi DD, Mele A, Fak JJ, Ule J, Kayikci M, Chi SW, Clark TA, Schweitzer AC, Blume JE, Wang X, Darnell JC, Darnell RB. Licatalosi DD, et al. Among authors: fak jj. Nature. 2008 Nov 27;456(7221):464-9. doi: 10.1038/nature07488. Epub 2008 Nov 2. Nature. 2008. PMID: 18978773 Free PMC article.

7

Rescuing Z+ agrin splicing in Nova null mice restores synapse formation and unmasks a physiologic defect in motor neuron firing.

Ruggiu M, Herbst R, Kim N, Jevsek M, Fak JJ, Mann MA, Fischbach G, Burden SJ, Darnell RB. Ruggiu M, et al. Among authors: fak jj. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3513-8. doi: 10.1073/pnas.0813112106. Epub 2009 Feb 12. Proc Natl Acad Sci U S A. 2009. PMID: 19221030 Free PMC article.

8

Integrative modeling defines the Nova splicing-regulatory network and its combinatorial controls.

Zhang C, Frias MA, Mele A, Ruggiu M, Eom T, Marney CB, Wang H, Licatalosi DD, Fak JJ, Darnell RB. Zhang C, et al. Among authors: fak jj. Science. 2010 Jul 23;329(5990):439-43. doi: 10.1126/science.1191150. Epub 2010 Jun 17. Science. 2010. PMID: 20558669 Free PMC article.

9

FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism.

Darnell JC, Van Driesche SJ, Zhang C, Hung KY, Mele A, Fraser CE, Stone EF, Chen C, Fak JJ, Chi SW, Licatalosi DD, Richter JD, Darnell RB. Darnell JC, et al. Among authors: fak jj. Cell. 2011 Jul 22;146(2):247-61. doi: 10.1016/j.cell.2011.06.013. Cell. 2011. PMID: 21784246 Free PMC article.

10

Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain.

Licatalosi DD, Yano M, Fak JJ, Mele A, Grabinski SE, Zhang C, Darnell RB. Licatalosi DD, et al. Among authors: fak jj. Genes Dev. 2012 Jul 15;26(14):1626-42. doi: 10.1101/gad.191338.112. Genes Dev. 2012. PMID: 22802532 Free PMC article.

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