Liu X - Search Results

1

Discovery and Crystallographic Studies of Trisubstituted Piperazine Derivatives as Non-Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity and Low Toxicity.

Gao S, Sylvester K, Song L, Claff T, Jing L, Woodson M, Weiße RH, Cheng Y, Schäkel L, Petry M, Gütschow M, Schiedel AC, Sträter N, Kang D, Xu S, Toth K, Tavis J, Tollefson AE, Müller CE, Liu X, Zhan P. Gao S, et al. Among authors: liu x. J Med Chem. 2022 Oct 13;65(19):13343-13364. doi: 10.1021/acs.jmedchem.2c01146. Epub 2022 Sep 15. J Med Chem. 2022. PMID: 36107752

2

Synthesis and anti-HIV activity evaluation of novel 2,4-disubstituted 7-methyl-1,1,3-trioxo-2,4-dihydro-pyrazolo-[4,5-e][1,2]thiadiazines.

Liu XY, Yan RZ, Wang Y, Zhan P, De Clercq E, Pannecouque C, Witvrouw M, Molina MT, Vega S. Liu XY, et al. Arch Pharm (Weinheim). 2008 Apr;341(4):216-22. doi: 10.1002/ardp.200700216. Arch Pharm (Weinheim). 2008. PMID: 18266290

3

Recent advances in antiviral activity of benzo/heterothiadiazine dioxide derivatives.

Zhan P, Liu X, De Clercq E. Zhan P, et al. Among authors: liu x. Curr Med Chem. 2008;15(15):1529-40. doi: 10.2174/092986708784638898. Curr Med Chem. 2008. PMID: 18537628 Review.

4

1,2,3-Thiadiazole thioacetanilides as a novel class of potent HIV-1 non-nucleoside reverse transcriptase inhibitors.

Zhan P, Liu X, Cao Y, Wang Y, Pannecouque C, De Clercq E. Zhan P, et al. Among authors: liu x. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5368-71. doi: 10.1016/j.bmcl.2008.09.055. Epub 2008 Sep 18. Bioorg Med Chem Lett. 2008. PMID: 18824350

5

Recent advances in the research of HIV-1 RNase H inhibitors.

Yu F, Liu X, Zhan P, De Clercq E. Yu F, et al. Among authors: liu x. Mini Rev Med Chem. 2008 Oct;8(12):1243-51. doi: 10.2174/138955708786141052. Mini Rev Med Chem. 2008. PMID: 18855738 Review.

6

Designed multiple ligands: an emerging anti-HIV drug discovery paradigm.

Zhan P, Liu X. Zhan P, et al. Among authors: liu x. Curr Pharm Des. 2009;15(16):1893-917. doi: 10.2174/138161209788453266. Curr Pharm Des. 2009. PMID: 19519431 Review.

7

Sulfanyltriazole/tetrazoles: a promising class of HIV-1 NNRTIs.

Zhan P, Li Z, Liu X, De Clercq E. Zhan P, et al. Among authors: liu x. Mini Rev Med Chem. 2009 Jul;9(8):1014-23. doi: 10.2174/138955709788681618. Mini Rev Med Chem. 2009. PMID: 19601897 Review.

8

Novel 1,2,3-thiadiazole derivatives as HIV-1 NNRTIs with improved potency: Synthesis and preliminary SAR studies.

Zhan P, Liu X, Li Z, Fang Z, Li Z, Wang D, Pannecouque C, Clercq ED. Zhan P, et al. Among authors: liu x. Bioorg Med Chem. 2009 Aug 15;17(16):5920-7. doi: 10.1016/j.bmc.2009.07.004. Epub 2009 Jul 7. Bioorg Med Chem. 2009. PMID: 19620009

9

Synthesis and anti-HIV activity evaluation of 2-(4-(naphthalen-2-yl)-1,2,3-thiadiazol-5-ylthio)-N-acetamides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.

Zhan P, Liu X, Fang Z, Li Z, Pannecouque C, De Clercq E. Zhan P, et al. Among authors: liu x. Eur J Med Chem. 2009 Nov;44(11):4648-53. doi: 10.1016/j.ejmech.2009.06.037. Epub 2009 Jul 4. Eur J Med Chem. 2009. PMID: 19628308

10

Synthesis and biological evaluation of imidazole thioacetanilides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.

Zhan P, Liu X, Zhu J, Fang Z, Li Z, Pannecouque C, Clercq ED. Zhan P, et al. Among authors: liu x. Bioorg Med Chem. 2009 Aug 15;17(16):5775-81. doi: 10.1016/j.bmc.2009.07.028. Epub 2009 Jul 18. Bioorg Med Chem. 2009. PMID: 19643613

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