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Discovery and Crystallographic Studies of Trisubstituted Piperazine Derivatives as Non-Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity and Low Toxicity.
Gao S, Sylvester K, Song L, Claff T, Jing L, Woodson M, Weiße RH, Cheng Y, Schäkel L, Petry M, Gütschow M, Schiedel AC, Sträter N, Kang D, Xu S, Toth K, Tavis J, Tollefson AE, Müller CE, Liu X, Zhan P. Gao S, et al. Among authors: woodson m. J Med Chem. 2022 Oct 13;65(19):13343-13364. doi: 10.1021/acs.jmedchem.2c01146. Epub 2022 Sep 15. J Med Chem. 2022. PMID: 36107752
Effects of Troponoids on Mitochondrial Function and Cytotoxicity.
Bradley DP, O'Dea AT, Woodson ME, Li Q, Ponzar NL, Knier A, Rogers BL, Murelli RP, Tavis JE. Bradley DP, et al. Antimicrob Agents Chemother. 2022 Jan 18;66(1):e0161721. doi: 10.1128/AAC.01617-21. Epub 2021 Oct 25. Antimicrob Agents Chemother. 2022. PMID: 34694883 Free PMC article.
Synthetic derivatives of the antifungal drug ciclopirox are active against herpes simplex virus 2.
Zangi M, Donald KA, Casals AG, Franson AD, Yu AJ, Marker EM, Woodson ME, Campbell SD, Mottaleb MA, Narayana Hajay Kumar TV, Reddy MS, Raghava Reddy LV, Sadhukhan SK, Griggs DW, Morrison LA, Meyers MJ. Zangi M, et al. Among authors: woodson me. Eur J Med Chem. 2022 Aug 5;238:114443. doi: 10.1016/j.ejmech.2022.114443. Epub 2022 May 14. Eur J Med Chem. 2022. PMID: 35635945 Free PMC article.
Discovery and Crystallographic Studies of Nonpeptidic Piperazine Derivatives as Covalent SARS-CoV-2 Main Protease Inhibitors.
Gao S, Song L, Claff T, Woodson M, Sylvester K, Jing L, Weiße RH, Cheng Y, Sträter N, Schäkel L, Gütschow M, Ye B, Yang M, Zhang T, Kang D, Toth K, Tavis J, Tollefson AE, Müller CE, Zhan P, Liu X. Gao S, et al. Among authors: woodson m. J Med Chem. 2022 Dec 22;65(24):16902-16917. doi: 10.1021/acs.jmedchem.2c01716. Epub 2022 Dec 7. J Med Chem. 2022. PMID: 36475694
67 results