Zorbaz T - Search Results

1

Altered levels of variant cholinesterase transcripts contribute to the imbalanced cholinergic signaling in Alzheimer's and Parkinson's disease.

Gok M, Madrer N, Zorbaz T, Bennett ER, Greenberg D, Bennett DA, Soreq H. Gok M, et al. Among authors: zorbaz t. Front Mol Neurosci. 2022 Sep 2;15:941467. doi: 10.3389/fnmol.2022.941467. eCollection 2022. Front Mol Neurosci. 2022. PMID: 36117917 Free PMC article.

2

Cholinergic blockade of neuroinflammation: from tissue to RNA regulators.

Zorbaz T, Madrer N, Soreq H. Zorbaz T, et al. Neuronal Signal. 2022 Feb 11;6(1):NS20210035. doi: 10.1042/NS20210035. eCollection 2022 Apr. Neuronal Signal. 2022. PMID: 35211331 Free PMC article. Review.

3

High-throughput morphometric and transcriptomic profiling uncovers composition of naïve and sensory-deprived cortical cholinergic VIP/CHAT neurons.

Yayon N, Amsalem O, Zorbaz T, Yakov O, Dubnov S, Winek K, Dudai A, Adam G, Schmidtner AK, Tessier-Lavigne M, Renier N, Habib N, Segev I, London M, Soreq H. Yayon N, et al. Among authors: zorbaz t. EMBO J. 2023 Jan 4;42(1):e110565. doi: 10.15252/embj.2021110565. Epub 2022 Nov 15. EMBO J. 2023. PMID: 36377476 Free PMC article.

4

Sex-specific declines in cholinergic-targeting tRNA fragments in the nucleus accumbens in Alzheimer's disease.

Shulman D, Dubnov S, Zorbaz T, Madrer N, Paldor I, Bennett DA, Seshadri S, Mufson EJ, Greenberg DS, Loewenstein Y, Soreq H. Shulman D, et al. Among authors: zorbaz t. Alzheimers Dement. 2023 Nov;19(11):5159-5172. doi: 10.1002/alz.13095. Epub 2023 May 9. Alzheimers Dement. 2023. PMID: 37158312 Free PMC article.

5

Pharmacokinetic Evaluation of Brain Penetrating Morpholine-3-hydroxy-2-pyridine Oxime as an Antidote for Nerve Agent Poisoning.

Zorbaz T, Mišetić P, Probst N, Žunec S, Zandona A, Mendaš G, Micek V, Maček Hrvat N, Katalinić M, Braïki A, Jean L, Renard PY, Gabelica Marković V, Kovarik Z. Zorbaz T, et al. ACS Chem Neurosci. 2020 Apr 1;11(7):1072-1084. doi: 10.1021/acschemneuro.0c00032. Epub 2020 Mar 11. ACS Chem Neurosci. 2020. PMID: 32105443

6

Cytotoxicity-related effects of imidazolium and chlorinated bispyridinium oximes in SH-SY5Y cells.

Zandona A, Zorbaz T, Miš K, Pirkmajer S, Katalinić M. Zandona A, et al. Among authors: zorbaz t. Arh Hig Rada Toksikol. 2022 Dec 30;73(4):277-284. doi: 10.2478/aiht-2022-73-3688. eCollection 2022 Dec 1. Arh Hig Rada Toksikol. 2022. PMID: 36607726 Free PMC article.

7

Halogen substituents enhance oxime nucleophilicity for reactivation of cholinesterases inhibited by nerve agents.

Zorbaz T, Malinak D, Hofmanova T, Maraković N, Žunec S, Hrvat NM, Andrys R, Psotka M, Zandona A, Svobodova J, Prchal L, Fingler S, Katalinić M, Kovarik Z, Musilek K. Zorbaz T, et al. Eur J Med Chem. 2022 Aug 5;238:114377. doi: 10.1016/j.ejmech.2022.114377. Epub 2022 Apr 27. Eur J Med Chem. 2022. PMID: 35526478

8

New Cinchona Oximes Evaluated as Reactivators of Acetylcholinesterase and Butyrylcholinesterase Inhibited by Organophosphorus Compounds.

Katalinić M, Zandona A, Ramić A, Zorbaz T, Primožič I, Kovarik Z. Katalinić M, et al. Among authors: zorbaz t. Molecules. 2017 Jul 22;22(7):1234. doi: 10.3390/molecules22071234. Molecules. 2017. PMID: 28737687 Free PMC article.

9

The estimation of oxime efficiency is affected by the experimental design of phosphylated acetylcholinesterase reactivation.

Maček Hrvat N, Zorbaz T, Šinko G, Kovarik Z. Maček Hrvat N, et al. Among authors: zorbaz t. Toxicol Lett. 2018 Sep 1;293:222-228. doi: 10.1016/j.toxlet.2017.11.022. Epub 2017 Nov 24. Toxicol Lett. 2018. PMID: 29180286

10

Potent 3-Hydroxy-2-Pyridine Aldoxime Reactivators of Organophosphate-Inhibited Cholinesterases with Predicted Blood-Brain Barrier Penetration.

Zorbaz T, Braïki A, Maraković N, Renou J, de la Mora E, Maček Hrvat N, Katalinić M, Silman I, Sussman JL, Mercey G, Gomez C, Mougeot R, Pérez B, Baati R, Nachon F, Weik M, Jean L, Kovarik Z, Renard PY. Zorbaz T, et al. Chemistry. 2018 Jul 5;24(38):9675-9691. doi: 10.1002/chem.201801394. Epub 2018 Jun 8. Chemistry. 2018. PMID: 29672968

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