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Imaging active site chemistry and protonation states: NMR crystallography of the tryptophan synthase α-aminoacrylate intermediate.
Holmes JB, Liu V, Caulkins BG, Hilario E, Ghosh RK, Drago VN, Young RP, Romero JA, Gill AD, Bogie PM, Paulino J, Wang X, Riviere G, Bosken YK, Struppe J, Hassan A, Guidoulianov J, Perrone B, Mentink-Vigier F, Chang CA, Long JR, Hooley RJ, Mueser TC, Dunn MF, Mueller LJ. Holmes JB, et al. Among authors: drago vn. Proc Natl Acad Sci U S A. 2022 Jan 11;119(2):e2109235119. doi: 10.1073/pnas.2109235119. Proc Natl Acad Sci U S A. 2022. PMID: 34996869 Free PMC article.