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Page 1
Metabolic collateral lethal target identification reveals MTHFD2 paralogue dependency in ovarian cancer.
Achreja A, Yu T, Mittal A, Choppara S, Animasahun O, Nenwani M, Wuchu F, Meurs N, Mohan A, Jeon JH, Sarangi I, Jayaraman A, Owen S, Kulkarni R, Cusato M, Weinberg F, Kweon HK, Subramanian C, Wicha MS, Merajver SD, Nagrath S, Cho KR, DiFeo A, Lu X, Nagrath D. Achreja A, et al. Nat Metab. 2022 Sep;4(9):1119-1137. doi: 10.1038/s42255-022-00636-3. Epub 2022 Sep 21. Nat Metab. 2022. PMID: 36131208
Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer.
Yang L, Moss T, Mangala LS, Marini J, Zhao H, Wahlig S, Armaiz-Pena G, Jiang D, Achreja A, Win J, Roopaimoole R, Rodriguez-Aguayo C, Mercado-Uribe I, Lopez-Berestein G, Liu J, Tsukamoto T, Sood AK, Ram PT, Nagrath D. Yang L, et al. Among authors: achreja a. Mol Syst Biol. 2014 May 5;10(5):728. doi: 10.1002/msb.20134892. Mol Syst Biol. 2014. PMID: 24799285 Free PMC article.
Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth.
Yang L, Achreja A, Yeung TL, Mangala LS, Jiang D, Han C, Baddour J, Marini JC, Ni J, Nakahara R, Wahlig S, Chiba L, Kim SH, Morse J, Pradeep S, Nagaraja AS, Haemmerle M, Kyunghee N, Derichsweiler M, Plackemeier T, Mercado-Uribe I, Lopez-Berestein G, Moss T, Ram PT, Liu J, Lu X, Mok SC, Sood AK, Nagrath D. Yang L, et al. Among authors: achreja a. Cell Metab. 2016 Nov 8;24(5):685-700. doi: 10.1016/j.cmet.2016.10.011. Cell Metab. 2016. PMID: 27829138 Free PMC article.
Amplification of USP13 drives ovarian cancer metabolism.
Han C, Yang L, Choi HH, Baddour J, Achreja A, Liu Y, Li Y, Li J, Wan G, Huang C, Ji G, Zhang X, Nagrath D, Lu X. Han C, et al. Among authors: achreja a. Nat Commun. 2016 Nov 28;7:13525. doi: 10.1038/ncomms13525. Nat Commun. 2016. PMID: 27892457 Free PMC article.
Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer.
Dey P, Baddour J, Muller F, Wu CC, Wang H, Liao WT, Lan Z, Chen A, Gutschner T, Kang Y, Fleming J, Satani N, Zhao D, Achreja A, Yang L, Lee J, Chang E, Genovese G, Viale A, Ying H, Draetta G, Maitra A, Wang YA, Nagrath D, DePinho RA. Dey P, et al. Among authors: achreja a. Nature. 2017 Feb 2;542(7639):119-123. doi: 10.1038/nature21052. Epub 2017 Jan 18. Nature. 2017. PMID: 28099419 Free PMC article.
Nitric Oxide: The Forgotten Child of Tumor Metabolism.
Salimian Rizi B, Achreja A, Nagrath D. Salimian Rizi B, et al. Among authors: achreja a. Trends Cancer. 2017 Sep;3(9):659-672. doi: 10.1016/j.trecan.2017.07.005. Epub 2017 Aug 18. Trends Cancer. 2017. PMID: 28867169 Free PMC article. Review.
The key role of extracellular vesicles in the metastatic process.
Zhao H, Achreja A, Iessi E, Logozzi M, Mizzoni D, Di Raimo R, Nagrath D, Fais S. Zhao H, et al. Among authors: achreja a. Biochim Biophys Acta Rev Cancer. 2018 Jan;1869(1):64-77. doi: 10.1016/j.bbcan.2017.11.005. Epub 2017 Nov 24. Biochim Biophys Acta Rev Cancer. 2018. PMID: 29175553 Free PMC article. Review.
Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism.
Collin de l'Hortet A, Takeishi K, Guzman-Lepe J, Morita K, Achreja A, Popovic B, Wang Y, Handa K, Mittal A, Meurs N, Zhu Z, Weinberg F, Salomon M, Fox IJ, Deng CX, Nagrath D, Soto-Gutierrez A. Collin de l'Hortet A, et al. Among authors: achreja a. Cell Metab. 2019 Aug 6;30(2):385-401.e9. doi: 10.1016/j.cmet.2019.06.017. Cell Metab. 2019. PMID: 31390551 Free PMC article.
30 results