Savastano A - Search Results

1

Molecular interactions of FG nucleoporin repeats at high resolution.

Ibáñez de Opakua A, Geraets JA, Frieg B, Dienemann C, Savastano A, Rankovic M, Cima-Omori MS, Schröder GF, Zweckstetter M. Ibáñez de Opakua A, et al. Among authors: savastano a. Nat Chem. 2022 Nov;14(11):1278-1285. doi: 10.1038/s41557-022-01035-7. Epub 2022 Sep 22. Nat Chem. 2022. PMID: 36138110 Free PMC article.

2

Disease-Associated Tau Phosphorylation Hinders Tubulin Assembly within Tau Condensates.

Savastano A, Flores D, Kadavath H, Biernat J, Mandelkow E, Zweckstetter M. Savastano A, et al. Angew Chem Int Ed Engl. 2021 Jan 11;60(2):726-730. doi: 10.1002/anie.202011157. Epub 2020 Nov 9. Angew Chem Int Ed Engl. 2021. PMID: 33017094 Free PMC article.

3

Nucleocapsid protein of SARS-CoV-2 phase separates into RNA-rich polymerase-containing condensates.

Savastano A, Ibáñez de Opakua A, Rankovic M, Zweckstetter M. Savastano A, et al. Nat Commun. 2020 Nov 27;11(1):6041. doi: 10.1038/s41467-020-19843-1. Nat Commun. 2020. PMID: 33247108 Free PMC article.

4

Solid-state NMR investigation of the involvement of the P2 region in tau amyloid fibrils.

Savastano A, Jaipuria G, Andreas L, Mandelkow E, Zweckstetter M. Savastano A, et al. Sci Rep. 2020 Dec 3;10(1):21210. doi: 10.1038/s41598-020-78161-0. Sci Rep. 2020. PMID: 33273615 Free PMC article.

5

Liquid-liquid phase separation of tau: From molecular biophysics to physiology and disease.

Rai SK, Savastano A, Singh P, Mukhopadhyay S, Zweckstetter M. Rai SK, et al. Among authors: savastano a. Protein Sci. 2021 Jul;30(7):1294-1314. doi: 10.1002/pro.4093. Epub 2021 May 14. Protein Sci. 2021. PMID: 33930220 Free PMC article. Review.

6

The pathogenic R5L mutation disrupts formation of Tau complexes on the microtubule by altering local N-terminal structure.

Cario A, Savastano A, Wood NB, Liu Z, Previs MJ, Hendricks AG, Zweckstetter M, Berger CL. Cario A, et al. Among authors: savastano a. Proc Natl Acad Sci U S A. 2022 Feb 15;119(7):e2114215119. doi: 10.1073/pnas.2114215119. Proc Natl Acad Sci U S A. 2022. PMID: 35135879 Free PMC article.

7

Contributions of the N-terminal intrinsically disordered region of the severe acute respiratory syndrome coronavirus 2 nucleocapsid protein to RNA-induced phase separation.

Zachrdla M, Savastano A, Ibáñez de Opakua A, Cima-Omori MS, Zweckstetter M. Zachrdla M, et al. Among authors: savastano a. Protein Sci. 2022 Sep;31(9):e4409. doi: 10.1002/pro.4409. Protein Sci. 2022. PMID: 36040256 Free PMC article.

8

Multivalent Tau/PSD-95 interactions arrest in vitro condensates and clusters mimicking the postsynaptic density.

Shen Z, Sun D, Savastano A, Varga SJ, Cima-Omori MS, Becker S, Honigmann A, Zweckstetter M. Shen Z, et al. Among authors: savastano a. Nat Commun. 2023 Oct 27;14(1):6839. doi: 10.1038/s41467-023-42295-2. Nat Commun. 2023. PMID: 37891164 Free PMC article.

9

N-truncated Aβ2-X starting with position two in sporadic Alzheimer's disease cases and two Alzheimer mouse models.

Savastano A, Klafki H, Haußmann U, Oberstein TJ, Muller P, Wirths O, Wiltfang J, Bayer TA. Savastano A, et al. J Alzheimers Dis. 2016;49(1):101-10. doi: 10.3233/JAD-150394. J Alzheimers Dis. 2016. PMID: 26529393

10

N-Truncated Aβ 2-X Starting with Position Two in Sporadic Alzheimer's Disease Cases and Two Alzheimer Mouse Models.

Savastano A, Klafki H, Haußmann U, Oberstein TJ, Muller P, Wirths O, Wiltfang J, Bayer TA. Savastano A, et al. J Alzheimers Dis. 2015 Sep 24. doi: 10.3233/JAD-150349. Online ahead of print. J Alzheimers Dis. 2015. PMID: 26444772

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