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Page 1
A Read/Write Mechanism Connects p300 Bromodomain Function to H2A.Z Acetylation.
Colino-Sanguino Y, Cornett EM, Moulder D, Smith GC, Hrit J, Cordeiro-Spinetti E, Vaughan RM, Krajewski K, Rothbart SB, Clark SJ, Valdés-Mora F. Colino-Sanguino Y, et al. Among authors: rothbart sb. iScience. 2019 Nov 22;21:773-788. doi: 10.1016/j.isci.2019.10.053. Epub 2019 Oct 31. iScience. 2019. PMID: 31727574 Free PMC article.
Histone H3.3 phosphorylation amplifies stimulation-induced transcription.
Armache A, Yang S, Martínez de Paz A, Robbins LE, Durmaz C, Cheong JQ, Ravishankar A, Daman AW, Ahimovic DJ, Klevorn T, Yue Y, Arslan T, Lin S, Panchenko T, Hrit J, Wang M, Thudium S, Garcia BA, Korb E, Armache KJ, Rothbart SB, Hake SB, Allis CD, Li H, Josefowicz SZ. Armache A, et al. Among authors: rothbart sb. Nature. 2020 Jul;583(7818):852-857. doi: 10.1038/s41586-020-2533-0. Epub 2020 Jul 22. Nature. 2020. PMID: 32699416 Free PMC article.
Single-genome analysis reveals heterogeneous association of the Herpes Simplex Virus genome with H3K27me2 and the reader PHF20L1 following infection of human fibroblasts.
Francois AK, Rohani A, Loftus M, Dochnal S, Hrit J, McFarlane S, Whitford A, Lewis A, Krakowiak P, Boutell C, Rothbart SB, Kashatus D, Cliffe AR. Francois AK, et al. Among authors: rothbart sb. bioRxiv [Preprint]. 2023 Dec 3:2023.12.03.569766. doi: 10.1101/2023.12.03.569766. bioRxiv. 2023. Update in: mBio. 2024 Apr 10;15(4):e0327823. doi: 10.1128/mbio.03278-23 PMID: 38076966 Free PMC article. Updated. Preprint.
UHRF1 ubiquitin ligase activity supports the maintenance of low-density CpG methylation.
Tiedemann RL, Hrit J, Du Q, Wiseman AK, Eden HE, Dickson BM, Kong X, Chomiak AA, Vaughan RM, Hebert JM, David Y, Zhou W, Baylin SB, Jones PA, Clark SJ, Rothbart SB. Tiedemann RL, et al. Among authors: rothbart sb. bioRxiv [Preprint]. 2024 Feb 16:2024.02.13.580169. doi: 10.1101/2024.02.13.580169. bioRxiv. 2024. Update in: Nucleic Acids Res. 2024 Dec 11;52(22):13733-13756. doi: 10.1093/nar/gkae1105 PMID: 38405904 Free PMC article. Updated. Preprint.
Single-genome analysis reveals a heterogeneous association of the herpes simplex virus genome with H3K27me2 and the reader PHF20L1 following infection of human fibroblasts.
Francois AK, Rohani A, Loftus M, Dochnal S, Hrit J, McFarlane S, Whitford A, Lewis A, Krakowiak P, Boutell C, Rothbart SB, Kashatus D, Cliffe AR. Francois AK, et al. Among authors: rothbart sb. mBio. 2024 Apr 10;15(4):e0327823. doi: 10.1128/mbio.03278-23. Epub 2024 Feb 27. mBio. 2024. PMID: 38411116 Free PMC article.
UHRF1 ubiquitin ligase activity supports the maintenance of low-density CpG methylation.
Tiedemann RL, Hrit J, Du Q, Wiseman AK, Eden HE, Dickson BM, Kong X, Chomiak AA, Vaughan RM, Tibben BM, Hebert JM, David Y, Zhou W, Baylin SB, Jones PA, Clark SJ, Rothbart SB. Tiedemann RL, et al. Among authors: rothbart sb. Nucleic Acids Res. 2024 Dec 11;52(22):13733-13756. doi: 10.1093/nar/gkae1105. Nucleic Acids Res. 2024. PMID: 39607687 Free PMC article.
DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states.
Liu Y, Hrit JA, Chomiak AA, Stransky S, Hoffman JR, Tiedemann RL, Wiseman AK, Kariapper LS, Dickson BM, Worden EJ, Fry CJ, Sidoli S, Rothbart SB. Liu Y, et al. Among authors: rothbart sb. Mol Cell. 2024 Nov 25:S1097-2765(24)00914-6. doi: 10.1016/j.molcel.2024.11.009. Online ahead of print. Mol Cell. 2024. PMID: 39631394 Free article.
Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1.
Harrison JS, Cornett EM, Goldfarb D, DaRosa PA, Li ZM, Yan F, Dickson BM, Guo AH, Cantu DV, Kaustov L, Brown PJ, Arrowsmith CH, Erie DA, Major MB, Klevit RE, Krajewski K, Kuhlman B, Strahl BD, Rothbart SB. Harrison JS, et al. Among authors: rothbart sb. Elife. 2016 Sep 6;5:e17101. doi: 10.7554/eLife.17101. Elife. 2016. PMID: 27595565 Free PMC article.
78 results