Mutch NJ - Search Results

1

Cryoprecipitate transfusion in trauma patients attenuates hyperfibrinolysis and restores normal clot structure and stability: Results from a laboratory sub-study of the FEISTY trial.

Morrow GB, Feller T, McQuilten Z, Wake E, Ariëns RAS, Winearls J, Mutch NJ, Laffan MA, Curry N. Morrow GB, et al. Among authors: mutch nj. Crit Care. 2022 Sep 26;26(1):290. doi: 10.1186/s13054-022-04167-x. Crit Care. 2022. PMID: 36163263 Free PMC article. Clinical Trial.

2

Consensus report on markers to distinguish procoagulant platelets from apoptotic platelets: communication from the Scientific and Standardization Committee of the ISTH.

Josefsson EC, Ramström S, Thaler J, Lordkipanidzé M; COAGAPO study group. Josefsson EC, et al. J Thromb Haemost. 2023 Aug;21(8):2291-2299. doi: 10.1016/j.jtha.2023.05.001. Epub 2023 May 10. J Thromb Haemost. 2023. PMID: 37172731 Free article.

3

Polyphosphate modifies the fibrin network and down-regulates fibrinolysis by attenuating binding of tPA and plasminogen to fibrin.

Mutch NJ, Engel R, Uitte de Willige S, Philippou H, Ariëns RA. Mutch NJ, et al. Blood. 2010 May 13;115(19):3980-8. doi: 10.1182/blood-2009-11-254029. Epub 2010 Mar 12. Blood. 2010. PMID: 20228273 Free article.

4

The antifibrinolytic function of factor XIII is exclusively expressed through α₂-antiplasmin cross-linking.

Fraser SR, Booth NA, Mutch NJ. Fraser SR, et al. Among authors: mutch nj. Blood. 2011 Jun 9;117(23):6371-4. doi: 10.1182/blood-2011-02-333203. Epub 2011 Apr 6. Blood. 2011. PMID: 21471521 Free PMC article.

5

Factor XIIa regulates the structure of the fibrin clot independently of thrombin generation through direct interaction with fibrin.

Konings J, Govers-Riemslag JW, Philippou H, Mutch NJ, Borissoff JI, Allan P, Mohan S, Tans G, Ten Cate H, Ariëns RA. Konings J, et al. Among authors: mutch nj. Blood. 2011 Oct 6;118(14):3942-51. doi: 10.1182/blood-2011-03-339572. Epub 2011 Aug 9. Blood. 2011. PMID: 21828145 Free article.

6

Polyphosphate delays fibrin polymerisation and alters the mechanical properties of the fibrin network.

Whyte CS, Chernysh IN, Domingues MM, Connell S, Weisel JW, Ariens RA, Mutch NJ. Whyte CS, et al. Among authors: mutch nj. Thromb Haemost. 2016 Oct 28;116(5):897-903. doi: 10.1160/TH16-01-0062. Epub 2016 Aug 25. Thromb Haemost. 2016. PMID: 27610454 Free PMC article.

7

uPA-mediated plasminogen activation is enhanced by polyphosphate.

Whyte CS, Mutch NJ. Whyte CS, et al. Among authors: mutch nj. Haematologica. 2021 Feb 1;106(2):522-531. doi: 10.3324/haematol.2019.237966. Haematologica. 2021. PMID: 32029503 Free PMC article.

8

Fibrinolytic abnormalities in acute respiratory distress syndrome (ARDS) and versatility of thrombolytic drugs to treat COVID-19.

Whyte CS, Morrow GB, Mitchell JL, Chowdary P, Mutch NJ. Whyte CS, et al. Among authors: mutch nj. J Thromb Haemost. 2020 Jul;18(7):1548-1555. doi: 10.1111/jth.14872. Epub 2020 Jun 3. J Thromb Haemost. 2020. PMID: 32329246 Free PMC article. Review.

9

Exposure of plasminogen and a novel plasminogen receptor, Plg-RKT, on activated human and murine platelets.

Whyte CS, Morrow GB, Baik N, Booth NA, Jalal MM, Parmer RJ, Miles LA, Mutch NJ. Whyte CS, et al. Among authors: mutch nj. Blood. 2021 Jan 14;137(2):248-257. doi: 10.1182/blood.2020007263. Blood. 2021. PMID: 32842150 Free PMC article.

10

Functional plasminogen activator inhibitor 1 is retained on the activated platelet membrane following platelet activation.

Morrow GB, Whyte CS, Mutch NJ. Morrow GB, et al. Among authors: mutch nj. Haematologica. 2020 Dec 1;105(12):2824-2833. doi: 10.3324/haematol.2019.230367. Haematologica. 2020. PMID: 33256381 Free PMC article.

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